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35,070 Result(s)
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Article
An Uncertainty-Quantification Machine Learning Framework for Data-Driven Three-Dimensional Mineral Prospectivity Map**
The uncertainty inherent in three-dimensional (3D) mineral prospectivity map** (MPM) encompasses (a) mineral system conceptual model uncertainty stemming from geological conceptual frameworks, (b) aleatoric ...
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COVID-19 Anti-Chinese Discrimination, Current Pandemic Stress, And Adolescents’ Mental Health
The current study investigated adolescents’ experiences of COVID-19 anti-Chinese discrimination (i.e., vicariously witnessed, directly experienced), the consequences for mental health, and the moderating role ...
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Exploring the potential of combining transcranial magnetic stimulation and electroencephalography to investigate mild cognitive impairment and Alzheimer’s disease: a systematic review
Transcranial magnetic stimulation (TMS) and electroencephalography (EEG) are non-invasive techniques used for neuromodulation and recording brain electrical activity, respectively. The integration of TMS-EEG h...
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Effects of antipsychotic drugs on energy metabolism
Schizophrenia (SCZ) is a complex neuropsychiatric disorder associated with altered bioenergetic pathways and mitochondrial dysfunction. Antipsychotic medications, both first and second-generation, are commonly...
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Human serum albumin-based drug-free macromolecular therapeutics induce apoptosis in chronic lymphocytic leukemia patient cells by crosslinking of CD20 and/or CD38 receptors
This study explores the efficacy of human serum albumin (HSA)-based Drug-Free Macromolecular Therapeutics (DFMT) in treating Chronic Lymphocytic Leukemia (CLL), a prevalent adult leukemia subtype. DFMT, a nove...
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Open AccessA bipolar disorder-associated missense variant alters adenylyl cyclase 2 activity and promotes mania-like behavior
The single nucleotide polymorphism rs13166360, causing a substitution of valine (Val) 147 to leucine (Leu) in the adenylyl cyclase 2 (ADCY2), has previously been associated with bipolar disorder (BD). Here we ...
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Open AccessGermline β−1,3-glucan deposits are required for female gametogenesis in Arabidopsis thaliana
Correct regulation of intercellular communication is a fundamental requirement for cell differentiation. In Arabidopsis thaliana, the female germline differentiates from a single somatic ovule cell that becomes e...
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Challenges in the Transition from Acute Hospital Care to Home for Spanish-Speaking Latino Patients with TBI and Families: Perspectives of Healthcare Providers and Interpreters
Language-based disparities negatively impact patient outcomes. Spanish-speaking Latino patients with traumatic brain injury (TBI) transitioning home from acute hospital care and their families have poor TBI-re...
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Open AccessGenetic and multi-omic resources for Alzheimer disease and related dementia from the Knight Alzheimer Disease Research Center
The Knight-Alzheimer Disease Research Center (Knight-ADRC) at Washington University in St. Louis has pioneered and led worldwide seminal studies that have expanded our clinical, social, pathological, and molec...
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A comprehensive review of state-of-charge and state-of-health estimation for lithium-ion battery energy storage systems
With the gradual transformation of energy industries around the world, the trend of industrial reform led by clean energy has become increasingly apparent. As a critical link in the new energy industry chain, ...
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Open AccessDefinitive engineering strength and fracture toughness of graphene through on-chip nanomechanics
Fail-safe design of devices requires robust integrity assessment procedures which are still absent for 2D materials, hence affecting transfer to applications. Here, a combined on-chip tension and cracking meth...
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Open AccessFormative research to understand food beliefs and practices relating to pregnancy on Kei Besar Island, Eastern Indonesia
Food-related beliefs and practices during pregnancy may contribute to the high prevalence of chronic energy deficiencies (CED) in Eastern Indonesia, particularly in Southeast Maluku regency, where 21.33% of pr...
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Open AccessHealth and wellbeing of staff working at higher education institutions globally during the post-COVID-19 pandemic period: evidence from a cross-sectional study
The ongoing global crisis of Higher Education (HE) institutions during the post-COVID-19 pandemic period has increased the likelihood of enduring psychological stressors for staff. This study aimed to identify...
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Open AccessEngineering hyaluronic acid-based nanoassemblies for monoclonal antibody delivery – design, characterization, and biological insights
The current spotlight of cancer therapeutics is shifting towards personalized medicine with the widespread use of monoclonal antibodies (mAbs). Despite their increasing potential, mAbs have an intrinsic limita...
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One-Dimensional Consolidation Modeling of Soil Surrounding Buried Geothermal Pipelines: Incorporating Heat Diffusion Processes
Thermal consolidation of soil is a significant concern in buried geothermal pipeline engineering. Soil consolidation begins immediately upon pipeline completion, while a stable temperature field does not insta...
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Open AccessSex-specific alterations in functional connectivity and network topology in patients with degenerative cervical myelopathy
Patients with degenerative cervical myelopathy (DCM) experience structural and functional brain reorganization. However, few studies have investigated the influence of sex on cerebral alterations. The present ...
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Open AccessSingle cell transcriptomes and multiscale networks from persons with and without Alzheimer’s disease
The emergence of single nucleus RNA sequencing (snRNA-seq) offers to revolutionize the study of Alzheimer’s disease (AD). Integration with complementary multiomics data such as genetics, proteomics and clinica...
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Open AccessA benchmark JWST near-infrared spectrum for the exoplanet WASP-39 b
Observing exoplanets through transmission spectroscopy supplies detailed information about their atmospheric composition, physics and chemistry. Before the James Webb Space Telescope (JWST), these observations...
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Open AccessEfficacy and safety of oral semaglutide vs sitagliptin in a predominantly Chinese population with type 2 diabetes uncontrolled with metformin: PIONEER 12, a double-blind, Phase IIIa, randomised trial
The aim of this study was to assess the efficacy and safety of oral semaglutide vs sitagliptin in a predominantly Chinese population with type 2 diabetes inadequately controlled with metformin treatment.
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SoccerNet 2023 challenges results
The SoccerNet 2023 challenges were the third annual video understanding challenges organized by the SoccerNet team. For this third edition, the challenges were composed of seven vision-based tasks split into t...