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Open AccessGenetic effects influencing risk for major depressive disorder in China and Europe
Major depressive disorder (MDD) is a common, complex psychiatric disorder and a leading cause of disability worldwide. Despite twin studies indicating its modest heritability (~30–40%), extensive heterogeneity...
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Article
Erratum: The protective effect of the obesity-associated rs9939609 A variant in fat mass- and obesity-associated gene on depression
Correction to: Molecular Psychiatry advance online publication, 20 November 2012; doi:10.1038/mp.2012.160 The published article contains several errors, as described below. 1. The second author should have bee...
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Article
The protective effect of the obesity-associated rs9939609 A variant in fat mass- and obesity-associated gene on depression
Candidate gene and genome-wide association studies have not identified common variants, which are reliably associated with depression. The recent identification of obesity predisposing genes that are highly ex...
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Article
Genome-wide association analysis of copy number variation in recurrent depressive disorder
Large, rare copy number variants (CNVs) have been implicated in a variety of psychiatric disorders, but the role of CNVs in recurrent depression is unclear. We performed a genome-wide analysis of large, rare C...
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Article
Depressive disorder moderates the effect of the FTO gene on body mass index
There is evidence that obesity-related disorders are increased among people with depression. Variation in the FTO (fat mass and obesity associated) gene has been shown to contribute to common forms of human obesi...
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Article
The risk for depression conferred by stressful life events is modified by variation at the serotonin transporter 5HTTLPR genotype: evidence from the Spanish PREDICT-Gene cohort
We report results from the PREDICT-Gene case-control study nested in a prospective cohort designed to identify predictors of the onset of depression among adult primary-care attendees. We tested the potential ...