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Article
Open AccessUncoupling of EGFR–RAS signaling and nuclear localization of YBX1 in colorectal cancer
The transcription factor YBX1 can act as a mediator of signals transmitted via the EGFR–RAS–MAPK axis. YBX1 expression has been associated with tumor progression and prognosis in multiple types of cancer. Immu...
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Article
Hypoxia-induced mixed-lineage leukemia 1 regulates glioma stem cell tumorigenic potential
Normal stem cells reside in functional niches critical for self-renewal and maintenance. Neural and hematopoietic stem cell niches, in particular, are characterized by restricted availability of oxygen and the...