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Article
Should Anti-EGFR Agents Be Used in Right-Sided RAS Wild-type Advanced Colorectal Cancer?
Colorectal cancer is the third most common cancer worldwide with a high mortality rate at the advanced stages of the disease. Treatment options are dependent on the stage of the disease, patients’ performance ...
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Chapter
Liquid Biopsy in Colorectal Cancer
Colorectal cancer (CRC) is the third most common cancer worldwide. Oncological CRC treatment is changing gradually replacing ancient drugs with the newest targeted agents (target therapy) and immunotherapy. Th...
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Chapter
CRC Liver Metastases
The liver is the most common metastatic site in patients with colorectal carcinoma (CRC) [1]. Twenty-five per cent (25 %) of CRC patients have clinically detectable liver metastases at the initial diagnosis an...
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Article
Impact of genetic variability and treatment-related factors on outcome in early breast cancer patients receiving (neo-) adjuvant chemotherapy with 5-fluorouracil, epirubicin and cyclophosphamide, and docetaxel
To assess the impact of patient-related factors, including genetic variability in genes involved in the metabolism of chemotherapeutic agents, on breast cancer-specific survival (BCSS) and recurrence-free int...
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Article
Standardized added metabolic activity (SAM) IN 18F-FDG PET assessment of treatment response in colorectal liver metastases
Standardized added metabolic activity (SAM) is a PET parameter for assessing the total metabolic load of malignant processes, avoiding partial volume effects and lesion segmentation. The potential role of this...
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Chapter
Chemotherapy
This chapter provides a synopsis of cancer chemotherapy in children. This can necessarily only be brief and further reading is recommended, since detailed knowledge of the clinical pharmacology and mechanisms ...