5 Result(s)
within
M Pandey
Biochemistry, general
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Article
Open AccessHomology and enzymatic requirements of microhomology-dependent alternative end joining
Nonhomologous DNA end joining (NHEJ) is one of the major double-strand break (DSB) repair pathways in higher eukaryotes. Recently, it has been shown that alternative NHEJ (A-NHEJ) occurs in the absence of clas...
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Article
Open AccessThe EIF4EBP3 translational repressor is a marker of CDC73 tumor suppressor haploinsufficiency in a parathyroid cancer syndrome
Germline mutation of the tumor suppressor gene CDC73 confers susceptibility to the hyperparathyroidism-jaw tumor syndrome associated with a high risk of parathyroid malignancy. Inactivating CDC73 mutations have a...
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Article
Taurine fails to protect against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced striatal dopamine depletion in mice
Taurine, a known antioxidant and neuroprotector has been investigated for its free radical scavenging action in vitro in isolated mitochondria, and tested whether it protects against 1-methyl-4-phenyl-1,2,3,6-...
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Article
Enteric Perforation—Single-Layer Closure
A hundred cases of enteric perforation, treated surgically by single- or double-layer closure, were studied prospectively. Mortality and morbidity rates were 10–18 and 37–42% and comparable in the two groups. ...
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Article
Xanthogranulomatous Cholecystitis
Xanthogranulomatous cholecystitis exists in asmall but significant proportion of routinecholecystectomy specimens. A few recent reports haveshown a possible association of this disease withcarcinoma of the gal...
