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Article
Open AccessCharacterisation of the new EpCAM-specific antibody HO-3: implications for trifunctional antibody immunotherapy of cancer
Epithelial cell adhesion molecule EpCAM is a transmembrane glycoprotein that is frequently overexpressed in a variety of carcinomas. This pan-carcinoma antigen has served as the target for a plethora of immuno...
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Article
Open AccessSpecific induction of pp125 focal adhesion kinase in human breast cancer
The pp125 focal adhesion kinase (FAK) is involved in integrin-mediated cell signalling and overexpressed in a variety of solid tumours. Focal adhesion kinase expression has been correlated to invasion and meta...