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    GAD1 (2q31.1), which encodes glutamic acid decarboxylase (GAD67), is associated with childhood-onset schizophrenia and cortical gray matter volume loss

    Postmortem brain studies have shown deficits in the cortical γ-aminobutyric acid (GABA) system in schizophrenic individuals. Expression studies have shown a decrease in the major GABA-synthesizing enzyme (glutami...

    A M Addington, M Gornick, J Duckworth, A Sporn, N Gogtay, A Bobb… in Molecular Psychiatry (2005)