5 Result(s)
within
M Fassan
English
Biomedicine, general
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Article
Open AccessDynamic changes of live/apoptotic circulating tumour cells as predictive marker of response to Sunitinib in metastatic renal cancer
Recently, we developed an apoptotic assay for expanding the monitoring capabilities of the circulating tumour cells (CTC) test during therapy. An automated platform for computing CTCs was integrated with a mAb...
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Article
Open AccessKey role of dual specificity kinase TTK in proliferation and survival of pancreatic cancer cells
Pancreatic ductal adenocarcinoma (PDAC) is among the most aggressive human malignancies with an overall 5-year survival rate of <5%. Despite significant advances in treatment of the disease during the past dec...
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Article
Genetic risk of subsequent esophageal cancer in lymphoma and breast cancer long-term survival patients: a pilot study
The occurrence of a second primary esophageal carcinoma (EC) in long-term cancer survivors may represent a late effect of previous radio-chemotherapeutic treatment. To identify the genetic factors that could i...
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Article
Tryptophan metabolism along the kynurenine and serotonin pathways reveals substantial differences in colon and rectal cancer
Induction of tryptophan (TRP) catabolism is an adaptation mechanism to restrict excessive acute immune response in tissues. In the tumour microenvironment, TRP catabolism’s dysregulation plays an important rol...
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Article
Open AccessEvaluating mismatch repair deficiency in colorectal cancer biopsy specimens
Mismatch repair (MMR) testing on all new cases of colorectal cancer (CRC) has customarily been preferably performed on surgical specimens, as more tissue is available; however, new clinical trials for the use ...
