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    Open Access

    GM2 ganglioside accumulation causes neuroinflammation and behavioral alterations in a mouse model of early onset Tay-Sachs disease

    Tay-Sachs disease (TSD), a type of GM2-gangliosidosis, is a progressive neurodegenerative lysosomal storage disorder caused by mutations in the α subunit of the lysosomal β-hexosaminidase enzyme. This disease is ...

    Seçil Akyıldız Demir, Zehra Kevser Timur, Nurselin Ateş… in Journal of Neuroinflammation (2020)

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