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  1. Article

    Open Access

    A systematic review of simulation studies which compare existing statistical methods to account for non-compliance in randomised controlled trials

    Non-compliance is a common challenge for researchers and may reduce the power of an intention-to-treat analysis. Whilst a per protocol approach attempts to deal with this issue, it can result in biased estimat...

    Lucy Abell, Francesca Maher, Angus C Jennings in BMC Medical Research Methodology (2023)