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  1. No Access

    Article

    Pentapeptide PYRAE triggers ER stress-mediated apoptosis of breast cancer cells in mice by targeting RHBDF1-BiP interaction

    Reinforced cellular responses to endoplasmic reticulum (ER) stress are caused by a variety of pathological conditions including cancers. Human rhomboid family-1 protein (RHBDF1), a multiple transmembrane prote...

    SungJu Ryu, Hui Long, **n-ling Zheng, Yuan-yuan Song… in Acta Pharmacologica Sinica (2024)

  2. No Access

    Article

    Interferon-γ produced by tumor-infiltrating NK cells and CD4+ T cells downregulates TNFSF15 expression in vascular endothelial cells

    Endothelial cells in an established vasculature secrete tumor necrosis factor superfamily-15 (TNFSF15; VEGI; TL1A) that functions as a negative modulator of neovascularization to maintain blood vessel stabilit...

    Yi Lu, **n Gu, Li Chen, Zhi Yao, Juan Song, **ulong Niu, Rong **ang… in Angiogenesis (2014)

  3. Article

    Introduction: A Special Issue on Tumor Microenvironment Research in China and Asia

    Lu-Yuan Li in Cancer Microenvironment (2012)

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  4. No Access

    Article

    TNFSF15 Modulates Neovascularization and Inflammation

    Tumor necrosis factor superfamily-15 (TNFSF15; also known as VEGI or TL1A) is a unique cytokine that functions in the modulation of vascular homeostasis and inflammation. TNFSF15 is expressed abundantly in est...

    Zhisong Zhang, Lu-Yuan Li in Cancer Microenvironment (2012)

  5. No Access

    Article

    Down-modulation of TNFSF15 in ovarian cancer by VEGF and MCP-1 is a pre-requisite for tumor neovascularization

    Persistent inflammation and neovascularization are critical to cancer development. In addition to upregulation of positive control mechanisms such as overexpression of angiogenic and inflammatory factors in th...

    Weimin Deng, **n Gu, Yi Lu, Chao Gu, Yangyang Zheng, Zhisong Zhang, Li Chen… in Angiogenesis (2012)

  6. No Access

    Article

    Vascular endothelial growth inhibitor (VEGI; TNFSF15) inhibits bone marrow-derived endothelial progenitor cell incorporation into Lewis lung carcinoma tumors

    Bone marrow (BM)-derived endothelial progenitor cells (EPC) have a critical role in tumor neovascularization. Vascular endothelial growth inhibitor (VEGI) is a member of the TNF superfamily (TNFSF15). We have ...

    Paulina H. Liang, Fang Tian, Yi Lu, Biyan Duan, Donna B. Stolz, Lu-Yuan Li in Angiogenesis (2011)