10,104 Result(s)
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Open AccessEfficient leather spreading operations by dual-arm robotic systems
To achieve precise gras** and spreading of irregular sheet-like soft objects (such as leather) by robots, this study addresses several challenges, including the irregularity of leather edges and the ambiguit...
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Open AccessB3galt5 functions as a PXR target gene and regulates obesity and insulin resistance by maintaining intestinal integrity
Pregnane X receptor (PXR) has been reported to regulate glycolipid metabolism. The dysfunction of intestinal barrier contributes to metabolic disorders. However, the role of intestinal PXR in metabolic disease...
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Open AccessExceptional figure of merit achieved in boron-dispersed GeTe-based thermoelectric composites
GeTe is a promising p-type material with increasingly enhanced thermoelectric properties reported in recent years, demonstrating its superiority for mid-temperature applications. In this work, the thermoelectr...
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Open AccessPeripheral immunity is associated with cognitive impairment after acute minor ischemic stroke and transient ischemic attack
Immunoinflammation is associated with the development of post-stroke cognitive impairment (PSCI), however, peripheral immunity has not been fully explored. We aimed to investigate the association between PSCI ...
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Open AccessNatural ventilation cooling effectiveness classification for building design addressing climate characteristics
The evaluation of natural ventilation potential for effective sustainable options and innovative green building design strategies is of great interest to architects, researchers and governments. From a retrosp...
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Open AccessDetecting localized damage in cantilevered structures under nonstationary ambient excitations via Gabor spectral mode transmissibility functions
A method based on Gabor spectral mode transmissibility functions (GSMTFs) is proposed to detect local damage in a cantilevered structure under nonstationary ambient excitations. Gabor transformation and singul...
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Open AccessGLP-1 receptor agonists’ impact on cardio-renal outcomes and mortality in T2D with acute kidney disease
Previous studies have explored the effects of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in reducing cardiovascular events in type 2 diabetes. Here we show that GLP-1 RAs are associated with lower r...
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Open AccessInterpretable machine learning for the prediction of death risk in patients with acute diquat poisoning
The aim of this study was to develop and validate predictive models for assessing the risk of death in patients with acute diquat (DQ) poisoning using innovative machine learning techniques. Additionally, pred...
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Open AccessGenetic and multi-omic resources for Alzheimer disease and related dementia from the Knight Alzheimer Disease Research Center
The Knight-Alzheimer Disease Research Center (Knight-ADRC) at Washington University in St. Louis has pioneered and led worldwide seminal studies that have expanded our clinical, social, pathological, and molec...
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Open AccessSliding mode control strategy based on disturbance observer for permanent magnet in-wheel motor
A novel sliding mode control(NSMC) strategy combined with a fast terminal sliding mode observer(FTSMO) is suggested in this paper to solve the parameter variation issue of permanent magnet in-wheel motor(PMIWM...
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Open AccessAssociation of volatile organic compound levels with chronic obstructive pulmonary diseases in NHANES 2013–2016
Volatile organic compounds (VOCs) represent a significant component of air pollution. However, studies evaluating the impact of VOC exposure on chronic obstructive pulmonary disease (COPD) have predominantly f...
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Open AccessDynamics of single-nuclei transcriptomic profiling of adipose tissue from diverse anatomical locations during mouse aging process
Adipose tissue plays critical roles in an individual’s aging process. In this research, we use single-nucleus RNA sequencing to create highly detailed transcriptional maps of subcutaneous adipose tissue and vi...
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Open AccessImmune cell landscapes are associated with high-grade serous ovarian cancer survival
High-grade serous ovarian cancer (HGSOC) is an aggressive disease known to develop resistance to chemotherapy. We investigated the prognostic significance of tumor cell states and potential mechanisms underlyi...
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Open AccessPlasmonic trimers designed as SERS-active chemical traps for subty** of lung tumors
Plasmonic materials can generate strong electromagnetic fields to boost the Raman scattering of surrounding molecules, known as surface-enhanced Raman scattering. However, these electromagnetic fields are hete...
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Open AccessDifferential potassium channel inhibitory activities of a novel thermostable degradation peptide BmKcug1a-P1 from scorpion medicinal material and its N-terminal truncated/restored peptides
Thermally stable full-length scorpion toxin peptides and partially degraded peptides with complete disulfide bond pairing are valuable natural peptide resources in traditional Chinese scorpion medicinal materi...
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Open AccessGlucose-6-phosphate dehydrogenase maintains redox homeostasis and biosynthesis in LKB1-deficient KRAS-driven lung cancer
Cancer cells depend on nicotinamide adenine dinucleotide phosphate (NADPH) to combat oxidative stress and support reductive biosynthesis. One major NADPH production route is the oxidative pentose phosphate pat...
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Open AccessEstablishment of a corneal ulcer prognostic model based on machine learning
Corneal infection is a major public health concern worldwide and the most common cause of unilateral corneal blindness. Toxic effects of different microorganisms, such as bacteria and fungi, worsen keratitis l...
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Open AccessThe selection of a surgical strategy for the treatment of adult degenerative scoliosis with "pear-shaped" decompression under open spinal endoscopy
The prognoses of patients who undergo open spinal endoscopy (OSE) decompression significantly differ by scoliosis type and symptom despite the use of uniform standards and procedures for the decompression surg...
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Open AccessGolpHCat (TMEM87A), a unique voltage-dependent cation channel in Golgi apparatus, contributes to Golgi-pH maintenance and hippocampus-dependent memory
Impaired ion channels regulating Golgi pH lead to structural alterations in the Golgi apparatus, such as fragmentation, which is found, along with cognitive impairment, in Alzheimer’s disease. However, the cau...
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Open AccessFew-shot RUL prediction for engines based on CNN-GRU model
In the realm of prognosticating the remaining useful life (RUL) of pivotal components, such as aircraft engines, a prevalent challenge persists where the available historical life data often proves insufficien...