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Tumour vasculature at single-cell resolution

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  1. Article

    Open Access

    Genomic and single-cell analyses reveal genetic signatures of swimming pattern and diapause strategy in jellyfish

    Jellyfish exhibit innovative swimming patterns that contribute to exploring the origins of animal locomotion. However, the genetic and cellular basis of these patterns remains unclear. Herein, we generated chr...

    Zhijun Dong, Fanghan Wang, Yali Liu, Yongxue Li, Haiyan Yu in Nature Communications (2024)

  2. Article

    Open Access

    Efficient leather spreading operations by dual-arm robotic systems

    To achieve precise gras** and spreading of irregular sheet-like soft objects (such as leather) by robots, this study addresses several challenges, including the irregularity of leather edges and the ambiguit...

    Yuan Huan, Gongchang Ren, Jiangong Sun, Guang **, Xujiang Ding in Scientific Reports (2024)

  3. Article

    Open Access

    B3galt5 functions as a PXR target gene and regulates obesity and insulin resistance by maintaining intestinal integrity

    Pregnane X receptor (PXR) has been reported to regulate glycolipid metabolism. The dysfunction of intestinal barrier contributes to metabolic disorders. However, the role of intestinal PXR in metabolic disease...

    **hang Zhang, Ya Huang, Hong Li, Pengfei Xu, Qinhui Liu, Yang Sun in Nature Communications (2024)

  4. Article

    Open Access

    Exceptional figure of merit achieved in boron-dispersed GeTe-based thermoelectric composites

    GeTe is a promising p-type material with increasingly enhanced thermoelectric properties reported in recent years, demonstrating its superiority for mid-temperature applications. In this work, the thermoelectr...

    Yilin Jiang, Bin Su, **cheng Yu, Zhanran Han, Haihua Hu in Nature Communications (2024)

  5. Article

    Open Access

    Peripheral immunity is associated with cognitive impairment after acute minor ischemic stroke and transient ischemic attack

    Immunoinflammation is associated with the development of post-stroke cognitive impairment (PSCI), however, peripheral immunity has not been fully explored. We aimed to investigate the association between PSCI ...

    PanPan Zhao, GuiMei Zhang, YongChun Wang, Chun**ao Wei, ZiCheng Wang in Scientific Reports (2024)

  6. Article

    Open Access

    Natural ventilation cooling effectiveness classification for building design addressing climate characteristics

    The evaluation of natural ventilation potential for effective sustainable options and innovative green building design strategies is of great interest to architects, researchers and governments. From a retrosp...

    Wen**g Li, **nhui Xu, Jiawei Yao, Qingchang Chen, Zhuoyang Sun in Scientific Reports (2024)

  7. Article

    Open Access

    Detecting localized damage in cantilevered structures under nonstationary ambient excitations via Gabor spectral mode transmissibility functions

    A method based on Gabor spectral mode transmissibility functions (GSMTFs) is proposed to detect local damage in a cantilevered structure under nonstationary ambient excitations. Gabor transformation and singul...

    HongJie Zhang, Qigang Sun, DanYu Li, Chen Li, Chunhui He, Gang Liu in Scientific Reports (2024)

  8. Article

    Open Access

    GLP-1 receptor agonists’ impact on cardio-renal outcomes and mortality in T2D with acute kidney disease

    Previous studies have explored the effects of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in reducing cardiovascular events in type 2 diabetes. Here we show that GLP-1 RAs are associated with lower r...

    Heng-Chih Pan, Jui-Yi Chen, Hsing-Yu Chen, Fang-Yu Yeh in Nature Communications (2024)

  9. Article

    Open Access

    Interpretable machine learning for the prediction of death risk in patients with acute diquat poisoning

    The aim of this study was to develop and validate predictive models for assessing the risk of death in patients with acute diquat (DQ) poisoning using innovative machine learning techniques. Additionally, pred...

    Huiyi Li, Zheng Liu, Wenming Sun, Tiegang Li, Xuesong Dong in Scientific Reports (2024)

  10. Article

    Open Access

    Genetic and multi-omic resources for Alzheimer disease and related dementia from the Knight Alzheimer Disease Research Center

    The Knight-Alzheimer Disease Research Center (Knight-ADRC) at Washington University in St. Louis has pioneered and led worldwide seminal studies that have expanded our clinical, social, pathological, and molec...

    Maria Victoria Fernandez, Menghan Liu, Aleksandra Beric, Matt Johnson in Scientific Data (2024)

  11. Article

    Open Access

    Sliding mode control strategy based on disturbance observer for permanent magnet in-wheel motor

    A novel sliding mode control(NSMC) strategy combined with a fast terminal sliding mode observer(FTSMO) is suggested in this paper to solve the parameter variation issue of permanent magnet in-wheel motor(PMIWM...

    Hao Huang, Chunfeng Yu, Zhonghua Sun, Yuanfeng Zhang, Zhibin Zhao in Scientific Reports (2024)

  12. Article

    Open Access

    Association of volatile organic compound levels with chronic obstructive pulmonary diseases in NHANES 2013–2016

    Volatile organic compounds (VOCs) represent a significant component of air pollution. However, studies evaluating the impact of VOC exposure on chronic obstructive pulmonary disease (COPD) have predominantly f...

    **angliang Liu, Yu Chang, Chengyao Xu, Yuguang Li, Yao Wang, Yao Sun in Scientific Reports (2024)

  13. Article

    Open Access

    Dynamics of single-nuclei transcriptomic profiling of adipose tissue from diverse anatomical locations during mouse aging process

    Adipose tissue plays critical roles in an individual’s aging process. In this research, we use single-nucleus RNA sequencing to create highly detailed transcriptional maps of subcutaneous adipose tissue and vi...

    Yujie Wu, Ying Sun, Long Chen, **ngyan Tong, Can Liu, Lu Lu in Scientific Reports (2024)

  14. Article

    Open Access

    Immune cell landscapes are associated with high-grade serous ovarian cancer survival

    High-grade serous ovarian cancer (HGSOC) is an aggressive disease known to develop resistance to chemotherapy. We investigated the prognostic significance of tumor cell states and potential mechanisms underlyi...

    Guoan Zhang, Yan Zhang, **g**g Zhang, **aohui Yang, Wenjie Sun in Scientific Reports (2024)

  15. Article

    Open Access

    Plasmonic trimers designed as SERS-active chemical traps for subty** of lung tumors

    Plasmonic materials can generate strong electromagnetic fields to boost the Raman scattering of surrounding molecules, known as surface-enhanced Raman scattering. However, these electromagnetic fields are hete...

    **ng Zhao, **ao**g Liu, Dexiang Chen, Guodong Shi, Guoqun Li in Nature Communications (2024)

  16. Article

    Open Access

    Differential potassium channel inhibitory activities of a novel thermostable degradation peptide BmKcug1a-P1 from scorpion medicinal material and its N-terminal truncated/restored peptides

    Thermally stable full-length scorpion toxin peptides and partially degraded peptides with complete disulfide bond pairing are valuable natural peptide resources in traditional Chinese scorpion medicinal materi...

    Chenhu Qin, Xuhua Yang, Zheng Zuo, Peixin Yuan, Fang Sun, Xudong Luo in Scientific Reports (2024)

  17. Article

    Open Access

    Glucose-6-phosphate dehydrogenase maintains redox homeostasis and biosynthesis in LKB1-deficient KRAS-driven lung cancer

    Cancer cells depend on nicotinamide adenine dinucleotide phosphate (NADPH) to combat oxidative stress and support reductive biosynthesis. One major NADPH production route is the oxidative pentose phosphate pat...

    Tai** Lan, Sara Arastu, Jarrick Lam, Hyungsin Kim, Wen** Wang in Nature Communications (2024)

  18. Article

    Open Access

    Establishment of a corneal ulcer prognostic model based on machine learning

    Corneal infection is a major public health concern worldwide and the most common cause of unilateral corneal blindness. Toxic effects of different microorganisms, such as bacteria and fungi, worsen keratitis l...

    Meng-Tong Wang, You-Ran Cai, Vlon Jang, Hong-Jian Meng, Ling-Bo Sun in Scientific Reports (2024)

  19. Article

    Open Access

    The selection of a surgical strategy for the treatment of adult degenerative scoliosis with "pear-shaped" decompression under open spinal endoscopy

    The prognoses of patients who undergo open spinal endoscopy (OSE) decompression significantly differ by scoliosis type and symptom despite the use of uniform standards and procedures for the decompression surg...

    Hongyan Wang, **n Liu, Yuefei Li, Jiabin Ren, Zhaozhong Sun, Ning Sun in Scientific Reports (2024)

  20. Article

    Open Access

    GolpHCat (TMEM87A), a unique voltage-dependent cation channel in Golgi apparatus, contributes to Golgi-pH maintenance and hippocampus-dependent memory

    Impaired ion channels regulating Golgi pH lead to structural alterations in the Golgi apparatus, such as fragmentation, which is found, along with cognitive impairment, in Alzheimer’s disease. However, the cau...

    Hyunji Kang, Ah-reum Han, Aihua Zhang, Hee** Jeong, Wuhyun Koh in Nature Communications (2024)

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