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  1. No Access

    Article

    Small Non-Coding sRNA53 Modulates the Quorum Sensing System to Enhance Drug Resistance in Escherichia coli Exposed to Heavy Ion and X-ray Irradiation

    Small non-coding RNAs (sRNAs, also called sncRNAs) known as gene expression regulatory factors are capable of modulating mRNA functions through complementary base pairing. A number of studies has shown that wh...

    S. J. Zhao, X. Y. Pang, Q. W. Zhao, X. Li in Molecular Biology (2024)

  2. No Access

    Article

    Promoter Mutation of the bZIP Transcription Factor BdABF Accelerates Flowering in Brachypodium distachyon

    Flowering time plays an important role in crop regional adaptation, yield and reproductive success. ABRE BINDING FACTORs (ABFs) are bZIP transcription factors that participate in various plant biological proce...

    B. J. Han, Z. J. Liu, W. M. Bai, F. T. Sun, Y. F. Niu, T. Y. Song… in Molecular Biology (2024)

  3. No Access

    Article

    Application of Cadherin cRNA Probes in Brains of Alzheimer’s Disease Mouse Model

    The cadherin superfamily molecules, functioning as cell adhesion molecules, are recognized to play roles in both physiological and pathological processes. The cadherin-based adherent junction (CAJ) is believed...

    H. Zhou, S. J. Du, F. Gendi, H. Y. Li, J. Fu, C. Chang in Molecular Biology (2024)

  4. No Access

    Article

    SoxB family genes delay regeneration and cause abnormal movement in Dugesia japonica

    SoxB subfamily is an important branch of Sox family and plays a key role in animal physiological process, but little is known about their function in planarian regeneration. This study aims to evaluate the functi...

    Yibo Yang, Ziyi Lin, Nannan Li, Ning Li, Dezeng Liu… in Molecular Genetics and Genomics (2024)

  5. No Access

    Article

    EMP1 correlated with cancer progression and immune characteristics in pan-cancer and ovarian cancer

    This study examines the prognostic role and immunological relevance of EMP1 (epithelial membrane protein-1) in a pan-cancer analysis, with a focus on ovarian cancer. Utilizing data from TCGA, CCLE, and GTEx da...

    Jun Zhang, **g Yang, **ng Li, Lin Mao, Yan Zhang… in Molecular Genetics and Genomics (2024)

  6. No Access

    Article

    Signature and function of plasma exosome-derived circular RNAs in patients with hypertensive intracerebral hemorrhage

    Intracerebral hemorrhage (ICH) is one of the major causes of death and disability, and hypertensive ICH (HICH) is the most common type of ICH. Currently, the outcomes of HICH patients remain poor after treatme...

    Kejie Chen, **aoyuan Cheng, Shanshan Yuan, Yang Sun… in Molecular Genetics and Genomics (2024)

  7. No Access

    Article

    Ginkgo biloba Leaf Polysaccharide Induces Autophagy and Modulates the Expression of Apoptosis Markers in Hepatocellular Carcinoma Cells

    Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and poses a severe threat to human health. Ginkgo biloba leaf polysaccharide (GBLP) is a bioactive component, and its sulphated derivativ...

    K. Li, Z. F. Yu, K. X. Zhang, Z. H. Li, X. C. Liu, B. Y. Li… in Molecular Biology (2024)

  8. No Access

    Article

    Microtubule-Associated Protein 9 Is a Potential Tumor Suppressor That Is Inactivated by Methylation in Cervical Cancer

    Cervical cancer is a malignant disease that seriously affects women’s health, and the cause of cervical cancer is complex. Microtubule-associated protein 9 (MAP9) localizes to the mitotic spindle and it plays ...

    P. Li, F. Wang, Y. Y. Gao, W. Zhang, Y. Zhang in Molecular Biology (2024)

  9. No Access

    Article

    SMURF1-Interference Effects Autophagy and Pulmonary Fibrosis through SMAD7 and the TGF-β1/SMAD Pathway

    SMAD-specific E3 ubiquitin proten ligase 1 (SMURF1) is involved in transforming growth factor (TGF)-β1/Smad pathway-mediated tissue fibrosis. However, its role in pulmonary fibrosis and the related molecular m...

    L. Lin, D. Xue, L.-M. Chen, Q.-Y. Wei, J.-H. Chen, Y. Li, X.-L. Ye… in Molecular Biology (2024)

  10. No Access

    Article

    Exploring the Potential Mechanism of Apoptosis Induced by MFSD8 in Endothelial Cells: an RNA Sequencing and Bioinformatics Analysis

    Neuronal ceroid lipofuscinoses (NCLs) belong to a group of inherited neurodegenerative disorders without effective treatments. Though loss-of-function in the MFSD8 gene resulting in a variant late-infantile subty...

    Q. **ang, Y. Liu, S. S. Jiang, Y. F. Chen, Y. X. Liu, D. W. Yang… in Molecular Biology (2024)

  11. No Access

    Article

    P3H4 Regulates Apoptosis and Autophagy of Breast Cancer Cells via BCL-2/BAX/Caspase-3 and AMPK/mTOR/ULK1 Signaling Pathways

    The role of prolyl 3-hydroxylase family member 4 (P3H4, or SC65) in breast cancer and the molecular mechanisms in which this protein was involved were investigated. For this purpose, microchips with cancerous ...

    T. Wang, M. M. Li, Z. Dong, D. M. Zhu in Molecular Biology (2024)

  12. Article

    Open Access

    Global Transcriptome Analysis Reveals Corresponding Genes and Key Pathways Involved in Oxidative Stress in Mouse Small Intestinal Cells

    Understanding the molecular mechanisms involved in the effects of oxidative stress in humans and animals is important to minimize the damage it causes, leading to various intestinal diseases. Our aim is to stu...

    Y. He, C. P. Feng, J. L. Li, R. Du in Molecular Biology (2024)

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  13. No Access

    Article

    lncCPSET1 acts as a scaffold for MLL2/COMPASS to regulate Bmp4 and promote the formation of chicken primordial germ cells

    Primordial germ cells (PGCs) are the ancestors of female and male germ cells. Recent studies have shown that long non-coding RNA (lncRNA) and histone methylation are key epigenetic factors affecting PGC format...

    Ying Ding, Chen Zhang, Qisheng Zuo, Kai **, Bichun Li in Molecular Genetics and Genomics (2024)

  14. No Access

    Article

    A novel imprinted locus on bovine chromosome 18 homologous with human chromosome 16q24.1

    Genomic imprinting is an epigenetic regulation mechanism in mammals resulting in the parentally dependent monoallelic expression of genes. Imprinting disorders in humans are associated with several congenital ...

    Haonan Huo, Cui Zhang, Kun Wang, Siwei Wang, Weina Chen… in Molecular Genetics and Genomics (2024)

  15. No Access

    Article

    Characterizing identity by descent segments in Chinese interpopulation unrelated individual pairs

    Identity by descent (IBD) segments, uninterrupted DNA segments derived from the same ancestral chromosomes, are widely used as indicators of relationships in genetics. A great deal of research focuses on IBD s...

    Qiqi Ji, Yining Yao, Zhimin Li, Zhihan Zhou… in Molecular Genetics and Genomics (2024)

  16. No Access

    Article

    Characterization of a novel heterozygous frameshift variant in NDP gene that causes familial exudative vitreoretinopathy in female patients

    Familial exudative vitreoretinopathy (FEVR) is a severe inherited disease characterized by defective retinal vascular development. With genetic and clinical heterogeneity, FEVR can be inherited in different pa...

    Mu Yang, Li Peng, Liting Lv, Erkuan Dai, Yunqi He… in Molecular Genetics and Genomics (2024)

  17. No Access

    Article

    Primer extension refractory PCR: an efficient and reliable genome walking method

    Genome walking, a molecular technique for obtaining unknown flanking genomic sequences from a known genomic sequence, has been broadly applied to determine transgenic sites, mine new genetic resources, and fil...

    Haixing Li, Zhiyu Lin, **nyue Guo, Zhenkang Pan, Hao Pan… in Molecular Genetics and Genomics (2024)

  18. No Access

    Article

    Novel MEI1 mutations cause chromosomal and DNA methylation abnormalities leading to embryonic arrest and implantation failure

    This study presents a case of a female infertile patient suffering from embryonic arrest and recurrent implantation failure. The primary objective was to assess the copy number variations (CNVs) and DNA methyl...

    **angli Wu, Yuqing Tian, Yiqi Yu, Xujun He, **aohua Tang… in Molecular Genetics and Genomics (2024)

  19. No Access

    Article

    The GaKAN2, a KANADI transcription factor, modulates stem trichomes in Gossypium arboreum

    GaKAN2, a member of the KANADI family, was found to be widely expressed in the cotton tissues and regulates trichome development through complex pathways.

    Xujiao Ren, Luying Yang, Yasir Muhammad, Yuxing **e… in Molecular Genetics and Genomics (2024)

  20. No Access

    Article

    Growth performance, lipid metabolism, and systemic immunity of weaned piglets were altered by buckwheat protein through the modulation of gut microbiota

    Tartary buckwheat protein (BWP) is well known for the wide-spectrum antibacterial activity and the lipid metabolism- regulating property; therefore, BWP can be applied as feed additives to improve the animal’s...

    Weilong Tu, Wansen Nie, **aohui Yao, Junjie Zhang… in Molecular Genetics and Genomics (2024)

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