3 Result(s)
within
Louise Harewood
Human Genetics
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Article
Open AccessLINE retrotransposons characterize mammalian tissue-specific and evolutionarily dynamic regulatory regions
To investigate the mechanisms driving regulatory evolution across tissues, we experimentally mapped promoters, enhancers, and gene expression in the liver, brain, muscle, and testis from ten diverse mammals.
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Article
Open AccessHi-C as a tool for precise detection and characterisation of chromosomal rearrangements and copy number variation in human tumours
Chromosomal rearrangements occur constitutionally in the general population and somatically in the majority of cancers. Detection of balanced rearrangements, such as reciprocal translocations and inversions, i...
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Protocol
Structural Variation and Its Effect on Expression
Structural variation, whether it is caused by copy number variants or present in a balanced form, such as reciprocal translocations and inversions, can have a profound and dramatic effect on the expression of ...
