1,414 Result(s)
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Liyan **ao
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Article
METTL3-modified lncRNA DSCAM-AS1 promotes breast cancer progression through inhibiting ferroptosis
Numerous studies have indicated that N6-methyladenosine (m6A) and lncRNAs play pivotal roles in human cancer. However, the underlying functions and mechanisms of m6A-lncRNA in the physiological processes of breas...
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Article
Multi-pole ratio single-winding pole-changing permanent magnet motor design and analysis
Pole-changing permanent magnet (PCPM) motors have advantages over traditional permanent magnet synchronous motors (PMSM) in high-speed applications. However, changing the pole number of a motor requires recons...
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Article
Analysis of wall thickness evolution and forming quality of sheet metal manufactured by wrinkles-free forming method
Sheet metal wrinkles-free forming method is a novel sheet metal forming technology which deforms a blank to the target part using low-melting point alloy (LMA) without the blank holder, increasing materials ut...
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Article
Thioredoxin-1 Protects Neurons Through Inhibiting NLRP1-Mediated Neuronal Pyroptosis in Models of Alzheimer’s Disease
Alzheimer’s disease (AD) is the most common neurodegenerative disease all over the world. In the last decade, accumulating proofs have evidenced that neuroinflammation is intimately implicated in the pathogene...
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A streamlined method to generate endothelial cells from human pluripotent stem cells via transient doxycycline-inducible ETV2 activation
The development of reliable methods for producing functional endothelial cells (ECs) is crucial for progress in vascular biology and regenerative medicine. In this study, we present a streamlined and efficient...
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Article
Essential Elements of Digital Citizenship: Insights from the Literature
This paper analyzed the existing literature on digital citizenship definitions and curricula to identify the essential elements of digital citizenship that must be addressed in a digital citizenship curriculum...
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Article
Open AccessNeoadjuvant chemotherapy with or without camrelizumab in resectable esophageal squamous cell carcinoma: the randomized phase 3 ESCORT-NEO/NCCES01 trial
Recent single-arm studies involving neoadjuvant camrelizumab, a PD-1 inhibitor, plus chemotherapy for resectable locally advanced esophageal squamous cell carcinoma (LA-ESCC) have shown promising results. This...
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Article
Open AccessYAP inhibition overcomes adaptive resistance in HER2-positive gastric cancer treated with trastuzumab via the AKT/mTOR and ERK/mTOR axis
Human epidermal growth factor receptor 2 (HER2)-positive gastric cancer (GC) is a heterogeneous GC subtype characterized by the overexpression of HER2. To date, few specific targeted therapies have demonstrate...
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Article
Multi-stage error compensation with closed-loop quality control in five-axis flank milling of sculptured surface
Machining efficiency and accuracy are subjected to higher requirements due to the increasingly widespread application of sculptured surface parts in the fields of aerospace, transportation, and energy. However...
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Article
Clothes-Eraser: clothing-aware controllable disentanglement for clothes-changing person re-identification
This paper conducts research on the problem of person re-identification in the context of urbanization and population growth, which holds significant application prospects in the field of computer vision. Trad...
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Article
Pure waterjet drilling thin CFRP laminate with [0/45/–45/90]2s stacking sequence
High-pressure pure waterjet (WJ) technology is widely used in the hole drilling process for carbon fiber–reinforced polymers (CFRP) laminates because of its high processing efficiency and zero heat affected zo...
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Article
Open AccessQuantitative parameter analysis of pretreatment dual-energy computed tomography in nasopharyngeal carcinoma cervical lymph node characteristics and prediction of radiotherapy sensitivity
Treatment efficacy may differ among patients with nasopharyngeal carcinoma (NPC) at similar tumor–node–metastasis stages. Moreover, end-of-treatment tumor regression is a reliable indicator of treatment sensit...
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Article
Open AccessData imbalance in cardiac health diagnostics using CECG-GAN
Heart disease is the world’s leading cause of death. Diagnostic models based on electrocardiograms (ECGs) are often limited by the scarcity of high-quality data and issues of data imbalance. To address these c...
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Article
Application of deep learning for characterizing microstructures in SBS modified asphalt
Microstructures in asphalt, often resembling bee structures, are pivotal in influencing asphalt performance and, by extension, sustainable fuel production. This study employs deep learning techniques to invest...
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Article
Open AccessSynthesis of borocarbonitride nanosheets from biomass for enhanced charge separation and hydrogen production
Borocarbonitride (BCN) materials have shown significant potential as photocatalysts for hydrogen production. However, traditional bulk BCN exhibits only moderate photocatalytic activity. In this study, we intr...
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Article
Open AccessSuccessful management of chromoblastomycosis utilizing conventional antifungal agents and imiquimod therapy
Chromoblastomycosis (CBM), a chronic fungal infection affecting the skin and subcutaneous tissues, is predominantly caused by dematiaceous fungi in tropical and subtropical areas. Characteristically, CBM prese...
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Article
Open AccessConnectivity of the insular subdivisions differentiates posttraumatic headache-associated from nonheadache-associated mild traumatic brain injury: an arterial spin labelling study
The insula is an important part of the posttraumatic headache (PTH) attributed to mild traumatic brain injury (mTBI) neuropathological activity pattern. It is composed of functionally different subdivisions an...
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Genomics and Epigenomics of Natural Killer/T Cell Lymphoma: Diagnostic, Prognostic, and Therapeutic Implications
Natural killer/T cell lymphoma (NKTCL), as an invasive subtype of non-Hodgkin lymphoma, is tightly linked with Epstein-Barr virus (EBV) infection. Genomic and epigenomic aberrations might be responsible for di...
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Article
Rational electrochemical design of hierarchical microarchitectures for SERS sensing applications
Electrochemical deposition has been widely used to prepare conformal coatings but has rarely been used to design well-defined micro/nanostructures. Here we report electrochemical synthesis of complex, hierarch...
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Article
MDA-YOLO Person: a 2D human pose estimation model based on YOLO detection framework
Human pose estimation aims to locate and predict the key points of the human body in images or videos. Due to the challenges of capturing complex spatial relationships and handling different body scales, accur...
