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Article
Simultaneous detection and characterization of toxigenic Clostridium difficile directly from clinical stool specimens
We employed a multiplex polymerase chain reaction (PCR) coupled with capillary electrophoresis (mPCR-CE) targeting six Clostridium difficile genes, including tpi, tcdA, tcdB, cdtA, cdtB, and a deletion in tcdC fo...
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Article
Open AccessEffectiveness of a multidimensional intervention program in improving occupational musculoskeletal disorders among intensive care unit nurses: a cluster-controlled trial with follow-up at 3 and 6 months
Intensive care unit (ICU) nurses are at high risk for work-related musculoskeletal disorders (WRMDs). Data on occupational injuries indicate the significance of WRMDs among ICU nurses. Intervention programs ha...
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Article
Human papillomavirus (HPV) integration signature in cervical lesions: identification of MACROD2 gene as HPV hot spot integration site
High-risk HPV is clearly associated with cervical cancer. Integration of HPV DNA into the host genome is considered a key event in driving cervical carcinogenesis. However, the mechanism on how HR-HPV integrat...
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Article
Development and validation of a nomogram model for central venous access device–related thrombosis in hospitalized children
This study aimed to develop and validate a nomogram model of central venous access device–related thrombosis (CRT) for hospitalized children. A total of 503 consecutive cases from a hospital in Changsha City, ...