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    IL-17-receptor-associated adaptor Act1 directly stabilizes mRNAs to mediate IL-17 inflammatory signaling

    Mechanisms that degrade inflammatory mRNAs are well known; however, stabilizing mechanisms are poorly understood. Here, we show that Act1, an interleukin-17 (IL-17)-receptor-complex adaptor, binds and stabiliz...

    Tomasz Herjan, Lingzi Hong, Jodi Bubenik, Katarzyna Bulek, Wen Qian… in Nature Immunology (2018)