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Article
PyFaceWipe: a new defacing tool for almost any MRI contrast
Defacing research MRI brain scans is often a mandatory step. With current defacing software, there are issues with Windows compatibility and researcher doubt regarding the adequacy of preservation of brain vox...
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Article
Kv3.1 Interaction with UBR5 Is Required for Chronic Inflammatory Pain
Chronic inflammatory pain caused by neuronal hyperactivity is a common and refractory disease. Kv3.1, a member of the Kv3 family of voltage-dependent K+ channels, is a major determinant of the ability of neurons ...
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Article
Open AccessGroup A Streptococcal meningitis in children: a short case series and systematic review
Group A streptococcal(GAS) meningitis is a severe disease with a high case fatality rate. In the era of increasing GAS meningitis, our understanding about this disease is limited.
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Article
Open AccessStructural variant landscapes reveal convergent signatures of evolution in sheep and goats
Sheep and goats have undergone domestication and improvement to produce similar phenotypes, which have been greatly impacted by structural variants (SVs). Here, we report a high-quality chromosome-level refere...
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Article
Open AccessUSP47 deficiency in mice modulates tumor infiltrating immune cells and enhances antitumor immune responses in prostate cancer
This study investigates the role of USP47, a deubiquitinating enzyme, in the tumor microenvironment and its impact on antitumor immune responses. Analysis of TCGA database revealed distinct expression patterns...
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Article
Open AccessDetection and diagnosis of automated breast ultrasound in patients with BI-RADS category 4 microcalcifications: a retrospective study
Automated Breast Ultrasound (AB US) has shown good application value and prospects in breast disease screening and diagnosis. The aim of the study was to explore the ability of AB US to detect and diagnose mam...
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Article
Open AccessP. gingivalis in oral-prostate axis exacerbates benign prostatic hyperplasia via IL-6/IL-6R pathway
Benign prostatic hyperplasia (BPH) is the most common disease in elderly men. There is increasing evidence that periodontitis increases the risk of BPH, but the specific mechanism remains unclear. This study a...
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Article
The catalytic triad of rice NARROW LEAF1 involves H234
NARROW LEAF1 (NAL1) exerts a multifaceted influence on leaf morphology and crop yield. Recent crystal study proposed that histidine 233 (H233) is part of the catalytic triad. Here we report that unlike suggested ...
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Article
Naoxueshu Oral Liquid Accelerates Post-Craniotomy Hematoma Absorption in Patients: An Open-Label, Multicenter, and Randomized Controlled Trial
To investigate whether Naoxueshu Oral Liquid (NXS) could promote hematoma absorption in post-craniotomy hematoma (PCH) patients.
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Article
Experimental Study on Pi** of Dike Foundation with Suspended Plastic Cutoff Wall Under Vertical Load
In this study, the influence of a vertical load on the deformation of a suspended plastic cutoff wall and the evolution of the pi** of a dike foundation were studied through model tests and numerical analysi...
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Article
Dynamic Treatment Strategy of Chinese Medicine for Metastatic Colorectal Cancer Based on Machine Learning Algorithm
To establish the dynamic treatment strategy of Chinese medicine (CM) for metastatic colorectal cancer (mCRC) by machine learning algorithm, in order to provide a reference for the selection of CM treatment str...
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Article
Open AccessPolicy scenario analysis of achieving the "dual carbon" goal for the road transportation sector in China
The goal of "dual carbon" has brought the pressure of reducing carbon emissions to the road transportation sector in China. This study aims to identify and analyze possible policy measures that would help to a...
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Article
Deep learning enables the discovery of a novel cuproptosis-inducing molecule for the inhibition of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the most common and deadly cancers in the world. The therapeutic outlook for HCC patients has significantly improved with the advent and development of systematic and t...
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Article
Open AccessStrong decays of \(T^a_{c{\bar{s}0}}(2900)^{++/0}\) as a fully open-flavor tetraquark state
We have studied the strong decay properties of the recently observed \(T^a_{c{\bar{s}0}}(2900)^{++/0}\) ...
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Article
Regulating surface base of LiCoO2 to inhibit side reactions between LiCoO2 and sulfide electrolyte
The interface instability between layered oxide cathode and sulfide electrolyte is a key point affecting the performance of sulfide-based all-solid-state lithium batteries. Coating with fast-ionic conductor an...
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Article
Open AccessPathExpSurv: pathway expansion for explainable survival analysis and disease gene discovery
In the field of biology and medicine, the interpretability and accuracy are both important when designing predictive models. The interpretability of many machine learning models such as neural networks is stil...
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Article
High-performance non-enzymatic glucose sensor based on Co3O4/rGO nanohybrid
There has been substantial interest in designing and fabricating electrochemical non-enzyme sensors for glucose detection with a focus on the nanocomposites used between metal oxide and the two-dimensional mat...
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Article
DHX9/DNA-tandem repeat-dependent downregulation of ciRNA-Fmn1 in the dorsal horn is required for neuropathic pain
Circular RNAs (ciRNAs) are emerging as new players in the regulation of gene expression. However, how ciRNAs are involved in neuropathic pain is poorly understood. Here, we identify the nervous-tissue-specific ci...
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Article
Open AccessP38-DAPK1 axis regulated LC3-associated phagocytosis (LAP) of microglia in an in vitro subarachnoid hemorrhage model
The phagocytosis and homeostasis of microglia play an important role in promoting blood clearance and improving prognosis after subarachnoid hemorrhage (SAH). LC3-assocaited phagocytosis (LAP) contributes to t...
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Article
Open AccessTwo body final states production in electron-positron annihilation and their contributions to (g − 2)μ
In this paper, we study the processes of e+e− annihilation into two body final states, either two pseudoscalar mesons or one meson with a photon. The hadronic vacuum polarization form factors are calculated withi...
