Skip to main content

and
  1. Article

    Open Access

    Effect of the transcription factor YY1 on the development of pancreatic endocrine and exocrine tumors: a narrative review

    Pancreatic tumors are classified into endocrine and exocrine types, and the clinical manifestations in patients are nonspecific. Most patients, especially those with pancreatic ductal adenocarcinoma (PDAC), ha...

    Qun Chen, Wu-Jun Wang, Yun-Xuan Jia, Hao Yuan, Peng-Fei Wu, Wan-Li Ge in Cell & Bioscience (2021)

  2. No Access

    Article

    Roundabout homolog 1 inhibits proliferation via the YY1-ROBO1-CCNA2-CDK2 axis in human pancreatic cancer

    Pancreatic cancer (PC) is highly malignant and has a high mortality with a 5-year survival rate of less than 8%. As a member of the roundabout immunoglobulin superfamily of proteins, ROBO1 plays an important r...

    Qun Chen, Peng Shen, Wan-Li Ge, Tao-Yue Yang, Wu-Jun Wang, Ling-Dong Meng in Oncogene (2021)

  3. Article

    Open Access

    The YY1/miR-548t-5p/CXCL11 signaling axis regulates cell proliferation and metastasis in human pancreatic cancer

    Pancreatic cancer (PC) is a malignant tumor with a poor prognosis and high mortality. However, the biological role of miR-548t-5p in PC has not been reported. In this study, we found that miR-548t-5p expressio...

    Wan-Li Ge, Qun Chen, Ling-Dong Meng, Xu-Min Huang, Guo-dong Shi in Cell Death & Disease (2020)