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  1. Article

    Open Access

    Characteristics of fault zones and their control on remaining oil distribution at the fault edge: a case study from the northern **ngshugang Anticline in the Daqing Oilfield, China

    Most major oil zones in the Daqing Oilfield have reached a later, high water cut stage, but oil recovery is still only approximately 35 %, and 50 % of reserves remain to be recovered. The remaining oil is prim...

    **ao-Fei Fu, **ao Lan, Ling-Dong Meng, Hai-Xue Wang, Zong-Bao Liu in Petroleum Science (2016)

  2. Article

    Open Access

    YY1 targets tubulin polymerisation-promoting protein to inhibit migration, invasion and angiogenesis in pancreatic cancer via p38/MAPK and PI3K/AKT pathways

    Pancreatic cancer (PDAC) is a highly invasive cancer with poor prognosis. Recent research has found that the transcription factor Yin Yang 1 (YY1) plays an inhibitory role in the development of pancreatic canc...

    Qun Chen, Chuang Yang, Lei Chen, **g-**g Zhang, Wan-Li Ge in British Journal of Cancer (2019)

  3. Article

    Open Access

    The YY1/miR-548t-5p/CXCL11 signaling axis regulates cell proliferation and metastasis in human pancreatic cancer

    Pancreatic cancer (PC) is a malignant tumor with a poor prognosis and high mortality. However, the biological role of miR-548t-5p in PC has not been reported. In this study, we found that miR-548t-5p expressio...

    Wan-Li Ge, Qun Chen, Ling-Dong Meng, Xu-Min Huang, Guo-dong Shi in Cell Death & Disease (2020)

  4. No Access

    Article

    Roundabout homolog 1 inhibits proliferation via the YY1-ROBO1-CCNA2-CDK2 axis in human pancreatic cancer

    Pancreatic cancer (PC) is highly malignant and has a high mortality with a 5-year survival rate of less than 8%. As a member of the roundabout immunoglobulin superfamily of proteins, ROBO1 plays an important r...

    Qun Chen, Peng Shen, Wan-Li Ge, Tao-Yue Yang, Wu-Jun Wang, Ling-Dong Meng in Oncogene (2021)

  5. Article

    Open Access

    Effect of the transcription factor YY1 on the development of pancreatic endocrine and exocrine tumors: a narrative review

    Pancreatic tumors are classified into endocrine and exocrine types, and the clinical manifestations in patients are nonspecific. Most patients, especially those with pancreatic ductal adenocarcinoma (PDAC), ha...

    Qun Chen, Wu-Jun Wang, Yun-Xuan Jia, Hao Yuan, Peng-Fei Wu, Wan-Li Ge in Cell & Bioscience (2021)