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    Article

    Roundabout homolog 1 inhibits proliferation via the YY1-ROBO1-CCNA2-CDK2 axis in human pancreatic cancer

    Pancreatic cancer (PC) is highly malignant and has a high mortality with a 5-year survival rate of less than 8%. As a member of the roundabout immunoglobulin superfamily of proteins, ROBO1 plays an important r...

    Qun Chen, Peng Shen, Wan-Li Ge, Tao-Yue Yang, Wu-Jun Wang, Ling-Dong Meng in Oncogene (2021)

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    Open Access

    YY1 targets tubulin polymerisation-promoting protein to inhibit migration, invasion and angiogenesis in pancreatic cancer via p38/MAPK and PI3K/AKT pathways

    Pancreatic cancer (PDAC) is a highly invasive cancer with poor prognosis. Recent research has found that the transcription factor Yin Yang 1 (YY1) plays an inhibitory role in the development of pancreatic canc...

    Qun Chen, Chuang Yang, Lei Chen, **g-**g Zhang, Wan-Li Ge in British Journal of Cancer (2019)