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Article
Open AccessEffect of the transcription factor YY1 on the development of pancreatic endocrine and exocrine tumors: a narrative review
Pancreatic tumors are classified into endocrine and exocrine types, and the clinical manifestations in patients are nonspecific. Most patients, especially those with pancreatic ductal adenocarcinoma (PDAC), ha...
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Article
Roundabout homolog 1 inhibits proliferation via the YY1-ROBO1-CCNA2-CDK2 axis in human pancreatic cancer
Pancreatic cancer (PC) is highly malignant and has a high mortality with a 5-year survival rate of less than 8%. As a member of the roundabout immunoglobulin superfamily of proteins, ROBO1 plays an important r...
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Article
Open AccessThe YY1/miR-548t-5p/CXCL11 signaling axis regulates cell proliferation and metastasis in human pancreatic cancer
Pancreatic cancer (PC) is a malignant tumor with a poor prognosis and high mortality. However, the biological role of miR-548t-5p in PC has not been reported. In this study, we found that miR-548t-5p expressio...
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Article
Open AccessYY1 targets tubulin polymerisation-promoting protein to inhibit migration, invasion and angiogenesis in pancreatic cancer via p38/MAPK and PI3K/AKT pathways
Pancreatic cancer (PDAC) is a highly invasive cancer with poor prognosis. Recent research has found that the transcription factor Yin Yang 1 (YY1) plays an inhibitory role in the development of pancreatic canc...
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Article
Open AccessCharacteristics of fault zones and their control on remaining oil distribution at the fault edge: a case study from the northern **ngshugang Anticline in the Daqing Oilfield, China
Most major oil zones in the Daqing Oilfield have reached a later, high water cut stage, but oil recovery is still only approximately 35 %, and 50 % of reserves remain to be recovered. The remaining oil is prim...