Skip to main content

1 Result(s)

within Linda Pudelko Remove this filter Chemistry Remove this filter

and

  1. No Access

    Article

    Development of a chemical probe against NUDT15

    The NUDIX hydrolase NUDT15 was originally implicated in sanitizing oxidized nucleotides, but was later shown to hydrolyze the active thiopurine metabolites, 6-thio-(d)GTP, thereby dictating the clinical respon...

    Si Min Zhang, Matthieu Desroses, Anna Hagenkort… in Nature Chemical Biology (2020)