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Open AccessExploring optimal Taxol® CYP725A4 activity in Saccharomyces cerevisiae
CYP725A4 catalyses the conversion of the first Taxol® precursor, taxadiene, to taxadiene-5α-ol (T5α-ol) and a range of other mono- and di-hydroxylated side products (oxygenated taxanes). Initially known to und...