11 Result(s)
within
Lian** Xue
Life Sciences, general
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Article
Open AccessUCHL3 induces radiation resistance and acquisition of mesenchymal phenotypes by deubiquitinating POLD4 in glioma stem cells
The high degree of intratumoral genomic heterogeneity is a major obstacle for glioblastoma (GBM) tumors, one of the most lethal human malignancies, and is thought to influence conventional therapeutic outcome...
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Article
Open AccessSTAT6 inhibits ferroptosis and alleviates acute lung injury via regulating P53/SLC7A11 pathway
Compelling evidences have revealed the emerging role of ferroptosis in the pathophysiological process of acute lung injury (ALI), but its modulation is not clear. Here, we identified that STAT6 acted as a crit...
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Article
Open AccessSTAT6 contributes to renal fibrosis by modulating PPARα-mediated tubular fatty acid oxidation
Lipid metabolism, especially fatty acid oxidation (FAO) dysfunction, is a major driver of renal fibrosis; however, the detailed regulatory mechanisms involved remain unclear. In this study, we showed that ther...
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Article
Multi-particle cryo-EM refinement with M visualizes ribosome-antibiotic complex at 3.5 Å in cells
Cryo-electron microscopy (cryo-EM) enables macromolecular structure determination in vitro and inside cells. In addition to aligning individual particles, accurate registration of sample motion and three-dimen...
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Article
Open AccessBroad-range and effective detection of human noroviruses by colloidal gold immunochromatographic assay based on the shell domain of the major capsid protein
Human noroviruses (HuNoVs) are a major cause of nonbacterial gastroenteritis in all age groups worldwide. HuNoVs can be detected in vitro using molecular assays such as RT-PCR and RT-qPCR. However, these molec...
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Article
Open AccessAuthor Correction: Liriodendron genome sheds light on angiosperm phylogeny and species–pair differentiation
In the Supplementary Information file originally published with this Letter, the authors mistakenly omitted Supplementary Table 14; this has now been amended.
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Article
Open AccessLiriodendron genome sheds light on angiosperm phylogeny and species–pair differentiation
The genus Liriodendron belongs to the family Magnoliaceae, which resides within the magnoliids, an early diverging lineage of the Mesangiospermae. However, the phylogenetic relationship of magnoliids with eudicot...
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Article
A genome-wide loss-of-function screening method for minimizing false-negatives caused by functional redundancy
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Article
Imaging without lenses: achievements and remaining challenges of wide-field on-chip microscopy
In this perspective, the authors present the basic features of lens-free computational imaging tools and report performance comparisons with conventional microscopy methods. They also discuss the challenges th...
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Article
Production of transgenic cashmere goat embryos expressing red fluorescent protein and containing IGF1 hair-follicle-cell specific expression cassette by somatic cell nuclear transfer
In the present study, cashmere goat fetal fibroblasts were transfected with pCDsR-KI, a hair-follicle-cell specific expression vector for insulin-like growth factor 1 (IGF1) that contains two markers for selec...
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Article
Mechanism of inversion metallogeny of quartz vein type gold deposits in the **aoqinling region
There are a lot of important gold-bearing quartz veins in the **aoqinling metamorphic core complex. The quartz veins are strictly controlled by shear zones. Stress analysis indicates that the metallizing proce...
