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  1. Article

    Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein

    An epidemic of pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is spreading worldwide. SARS-CoV-2 relies on its spike protein to invade host cells by interacting with the human...

    Lin Wang, Yan Wu, Sheng Yao, Huan Ge, Ya Zhu, Kun Chen in Acta Pharmacologica Sinica (2022)

  2. Article

    A multi-targeting drug design strategy for identifying potent anti-SARS-CoV-2 inhibitors

    The COVID-19, caused by SARS-CoV-2, is threatening public health, and there is no effective treatment. In this study, we have implemented a multi-targeted anti-viral drug design strategy to discover highly pot...

    Peng-xuan Ren, Wei-juan Shang, Wan-chao Yin, Huan Ge in Acta Pharmacologica Sinica (2022)

  3. Article

    A homolog of glyceraldehyde-3-phosphate dehydrogenase from Riemerella anatipestifer is an extracellular protein and exhibits biological activity

    Riemerella anatipestifer is the causative agent of septicemia anserum exsudativa in ducks. Its pathogenesis and virulence factors are still unclear. The glycolytic enzyme, glyceraldehyde-3-phosphate dehydrogenas...

    Ji-ye Gao, Cui-lian Ye, Li-li Zhu in Journal of Zhejiang University-SCIENCE B (2014)