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The post-translational modification of Fascin: impact on cell biology and its associations with inhibiting tumor metastasis

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  1. Article

    Open Access

    Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

    Anillin (ANLN) is a mitosis-related protein that promotes contractile ring formation and cytokinesis, but its cell cycle-dependent degradation mechanisms in cancer cells remain unclear. Here, we show that high...

    Yu-Fei Cao, Lei **e, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi… in Cell Death & Differentiation (2023)

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  2. Article

    Open Access

    Blocking STAT3 signaling augments MEK/ERK inhibitor efficacy in esophageal squamous cell carcinoma

    Esophageal squamous cell carcinoma (ESCC) is one of the world’s leading causes of death, and its primary clinical therapy relies on surgical resection, chemotherapy, radiotherapy, and chemoradiotherapy. Althou...

    Zhen-Yuan Zheng, Man-Yu Chu, Wan Lin, Ya-Qi Zheng, **u-E Xu… in Cell Death & Disease (2022)

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  3. Article

    Open Access

    SLC52A3 expression is activated by NF-κB p65/Rel-B and serves as a prognostic biomarker in esophageal cancer

    The human riboflavin transporter-3 (encoded by SLC52A3) plays a prominent role in riboflavin absorption. Interestingly, abnormal expression patterns of SLC52A3 in multiple types of human cancers have been recentl...

    Lin Long, **ao-**ao Pang, Fei Lei, Jia-Sheng Zhang… in Cellular and Molecular Life Sciences (2018)

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