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  1. Article

    Open Access

    Neferine inhibits BMECs pyroptosis and maintains blood–brain barrier integrity in ischemic stroke by triggering a cascade reaction of PGC-1α

    Blood–brain barrier disruption is a critical pathological event in the progression of ischemic stroke (IS). Most studies regarding the therapeutic potential of neferine (Nef) on IS have focused on neuroprotect...

    Zi-jian Zheng, Li-zhi Zhu, Han Qiu, Wu-yin-xiao Zheng, Peng-tao You in Scientific Reports (2024)

  2. Article

    Open Access

    A chromosome-level genome assembly of the spider mite Tetranychus piercei McGregor

    Despite the rapid advances in sequencing technology, limited genomic resources are currently available for phytophagous spider mites, which include many important agricultural pests. One of these pests is Tetrany...

    Lei Chen, **n-Yue Yu, Feng Zhang, Hua-Meng Zhang, Li-Xue Guo, Lu Ren in Scientific Data (2024)

  3. Article

    Open Access

    Explainable machine learning for early predicting treatment failure risk among patients with TB-diabetes comorbidity

    The present study aims to assess the treatment outcome of patients with diabetes and tuberculosis (TB-DM) at an early stage using machine learning (ML) based on electronic medical records (EMRs). A total of 42...

    An-zhou Peng, **ang-Hua Kong, Song-tao Liu, Hui-fen Zhang in Scientific Reports (2024)

  4. No Access

    Article

    Ligand-channel-enabled ultrafast Li-ion conduction

    Li-ion batteries (LIBs) for electric vehicles and aviation demand high energy density, fast charging and a wide operating temperature range, which are virtually impossible because they require electrolytes to ...

    Di Lu, Ruhong Li, Muhammad Mominur Rahman, Pengyun Yu, Ling Lv, Sheng Yang in Nature (2024)

  5. Article

    Open Access

    Synthesis and superconductivity in yttrium-cerium hydrides at high pressures

    Further increasing the critical temperature and/or decreasing the stabilized pressure are the general hopes for the hydride superconductors. Inspired by the low stabilized pressure associated with Ce 4f electrons...

    Liu-Cheng Chen, Tao Luo, Zi-Yu Cao, Philip Dalladay-Simpson in Nature Communications (2024)

  6. Article

    Open Access

    Epidemiologic changes of a longitudinal surveillance study spanning 51 years of scrub typhus in mainland China

    Scrub typhus may be one of the world’s most prevalent, neglected and serious, but easily treatable, febrile diseases. It has become a significant potential threat to public health in China. In this study we us...

    Pei-Ying Peng, Hui-Ying Duan, Lei Xu, Lin-Tao Zhang, Ji-Qin Sun in Scientific Reports (2024)

  7. Article

    Open Access

    Machine learning-based prediction model for myocardial ischemia under high altitude exposure: a cohort study

    High altitude exposure increases the risk of myocardial ischemia (MI) and subsequent cardiovascular death. Machine learning techniques have been used to develop cardiovascular disease prediction models, but no...

    Yu Chen, **n Zhang, Qing Ye, **n Zhang, Ning Cao, Shao-Ying Li in Scientific Reports (2024)

  8. Article

    Open Access

    Surplus fatty acid synthesis increases oxidative stress in adipocytes and induces lipodystrophy

    Adipocytes are the primary sites for fatty acid storage, but the synthesis rate of fatty acids is very low. The physiological significance of this phenomenon remains unclear. Here, we show that surplus fatty a...

    Li Weng, Wen-Shuai Tang, Xu Wang, Yingyun Gong, Changqin Liu in Nature Communications (2024)

  9. Article

    Open Access

    A 3-year follow-up clinical study on the preservation for vitality of involved tooth in jaw cysts through an innovative method

    Jaw cysts commonly affect the oral and maxillofacial region, involving adjacent tooth roots. The management of these teeth, particularly regarding root canal therapy and apicoectomy, lacks consensus. This stud...

    Gang Niu, GongHang Zhang, Jia-min Chen, Tao Wang, Ye Wu, You-Guang Lu in Scientific Reports (2024)

  10. Article

    Open Access

    Excess PrPC inhibits muscle cell differentiation via miRNA-enhanced liquid–liquid phase separation implicated in myopathy

    The cellular prion protein (PrPC) is required for skeletal muscle function. Here, we report that a higher level of PrPC accumulates in the cytoplasm of the skeletal muscle of six myopathy patients compared to con...

    **g Tao, Yan** Zeng, Bin Dai, Yin Liu, **aohan Pan in Nature Communications (2023)

  11. Article

    Open Access

    Co-option of a non-retroviral endogenous viral element in planthoppers

    Non-retroviral endogenous viral elements (nrEVEs) are widely dispersed throughout the genomes of eukaryotes. Although nrEVEs are known to be involved in host antiviral immunity, it remains an open question whe...

    Hai-Jian Huang, Yi-Yuan Li, Zhuang-**n Ye, Li-Li Li, Qing-Ling Hu in Nature Communications (2023)

  12. Article

    Open Access

    PH13 improves soybean shade traits and enhances yield for high-density planting at high latitudes

    Shading in combination with extended photoperiods can cause exaggerated stem elongation (ESE) in soybean, leading to lodging and reduced yields when planted at high-density in high-latitude regions. However, t...

    Chao Qin, Ying-hui Li, Delin Li, Xueru Zhang, Ling** Kong in Nature Communications (2023)

  13. Article

    Open Access

    A radiomics model based on magnetic resonance imaging to predict cytokeratin 7/19 expression and liver fluke infection of hepatocellular carcinoma

    Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer. HCC with liver fluke infection could harbor unique biological behaviors. This study was aimed at investigating radiomics features...

    Jun-Qi Liu, **g Wang, **a-Ling Huang, Tian-Yi Liang, **n Zhou in Scientific Reports (2023)

  14. Article

    Open Access

    Chiral recognition of neutral guests by chiral naphthotubes with a bis-thiourea endo-functionalized cavity

    Develo** chiral receptors with an endo-functionalized cavity for chiral recognition is of great significance in the field of molecular recognition. This study presents two pairs of chiral naphthotubes contai...

    Song-Meng Wang, Yan-Fang Wang, Li** Huang, Li-Shuo Zheng in Nature Communications (2023)

  15. Article

    Open Access

    Temperature-dependent interphase formation and Li+ transport in lithium metal batteries

    High-performance Li-ion/metal batteries working at a low temperature (i.e., <−20 °C) are desired but hindered by the sluggish kinetics associated with Li+ transport and charge transfer. Herein, the temperature-de...

    Suting Weng, **ao Zhang, Gao**g Yang, Simeng Zhang, Bingyun Ma in Nature Communications (2023)

  16. Article

    Open Access

    LILRB2/PirB mediates macrophage recruitment in fibrogenesis of nonalcoholic steatohepatitis

    Inhibition of immunocyte infiltration and activation has been suggested to effectively ameliorate nonalcoholic steatohepatitis (NASH). Paired immunoglobulin-like receptor B (PirB) and its human ortholog recept...

    Dan-Pei Li, Li Huang, Ran-Ran Kan, **ao-Yu Meng, Shu-Yun Wang in Nature Communications (2023)

  17. Article

    Open Access

    Benign esophageal stricture model construction and mechanism exploration

    Esophageal stricture is a debilitating condition that negatively impacts patients' quality of life after undergoing endoscopic mucosal resection (EMR). Despite its significance, this disease remains underexplo...

    Rui Wu, Min Fu, Hui-Min Tao, Tao Dong, Wen-Tao Fan, Li-Li Zhao in Scientific Reports (2023)

  18. Article

    Open Access

    Deep learning and ultrasound feature fusion model predicts the malignancy of complex cystic and solid breast nodules with color Doppler images

    This study aimed to evaluate the performance of traditional-deep learning combination model based on Doppler ultrasound for diagnosing malignant complex cystic and solid breast nodules. A conventional statisti...

    Han Liu, Chun-Jie Hou, **g-Lan Tang, Li-Tao Sun, Ke-Feng Lu in Scientific Reports (2023)

  19. Article

    Open Access

    Ketone α-alkylation at the more-hindered site

    Control of the regioselectivity of α-alkylation of carbonyl compounds is a longstanding topic of research in organic chemistry. By using stoichiometric bulky strong bases and carefully adjusting the reaction c...

    Ming-Ming Li, Tianze Zhang, Lei Cheng, Wei-Guo **ao, **-Tao Ma in Nature Communications (2023)

  20. Article

    Open Access

    Umbilical cord blood exosomes from very preterm infants with bronchopulmonary dysplasia aggravate lung injury in mice

    Bronchopulmonary dysplasia (BPD) is characterized by abnormal development of the blood vessels and alveoli in lungs, which largely occurs in premature infants. Exosomes (EXO) from very preterm infants (VPI) wi...

    **n-qi Zhong, Tao-fang Hao, Qi-jiong Zhu, **g Zheng, Mao-fei Zheng in Scientific Reports (2023)

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