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The role of systemic inflammatory response index (SIRI) and tumor-infiltrating lymphocytes (TILs) in the prognosis of patients with laryngeal squamous cell carcinoma

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  1. Article

    Open Access

    Neoadjuvant nivolumab with or without platinum-doublet chemotherapy based on PD-L1 expression in resectable NSCLC (CTONG1804): a multicenter open-label phase II study

    This prospective multicenter phase II study evaluated the clinical efficacy of neoadjuvant nivolumab-exclusive (N) and nivolumab–chemotherapy (N/C) combinations based on PD-L1 expression. Eligible patients exh...

    Si-Yang Liu, Song Dong, Xue-Ning Yang in Signal Transduction and Targeted Therapy (2023)

  2. Article

    Open Access

    Integrating single-cell RNA sequencing with spatial transcriptomics reveals immune landscape for interstitial cystitis

    Interstitial cystitis (IC) is a severely debilitating and chronic disorder with unclear etiology and pathophysiology, which makes the diagnosis difficult and treatment challenging. To investigate the role of i...

    Liao Peng, ** **, Bo-ya Li, **ao Zeng in Signal Transduction and Targeted Therapy (2022)

  3. Article

    Correction to: Progression-free survival at 24 months and subsequent survival of patients with extranodal NK/T-cell lymphoma: a China Lymphoma Collaborative Group (CLCG) study

    Yong Yang, Ying Wang, **n Liu, **a He, Li-Ling Zhang, Gang Wu, Bao-Lin Qu in Leukemia (2021)

  4. Article

    Open Access

    Detection of an anti-angina therapeutic module in the effective population treated by a multi-target drug Danhong injection: a randomized trial

    It’s a challenge for detecting the therapeutic targets of a polypharmacological drug from variations in the responsed networks in the differentiated populations with complex diseases, as stable coronary heart ...

    Jun Liu, Dan-Dan Li, Wei Dong, Yu-Qi Liu in Signal Transduction and Targeted Therapy (2021)

  5. Article

    Open Access

    Progression-free survival at 24 months and subsequent survival of patients with extranodal NK/T-cell lymphoma: a China Lymphoma Collaborative Group (CLCG) study

    Limited evidence supports the use of early endpoints to evaluate the success of initial treatment of extranodal NK/T-cell lymphoma (ENKTCL) in the modern era. We aim to analyze progression-free survival at 24 ...

    Yong Yang, Ying Wang, **n Liu, **a He, Li-Ling Zhang, Gang Wu, Bao-Lin Qu in Leukemia (2021)

  6. Article

    Open Access

    Safety and efficacy of meplazumab in healthy volunteers and COVID-19 patients: a randomized phase 1 and an exploratory phase 2 trial

    Recent evidence suggests that CD147 serves as a novel receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Blocking CD147 via anti-CD147 antibody could suppress the in vitro SAR...

    Huijie Bian, Zhao-Hui Zheng, Ding Wei in Signal Transduction and Targeted Therapy (2021)

  7. Article

    Open Access

    Validation of nomogram-revised risk index and comparison with other models for extranodal nasal-type NK/T-cell lymphoma in the modern chemotherapy era: indication for prognostication and clinical decision-making

    Derived from our original nomogram study by using the risk variables from multivariable analyses in the derivation cohort of 1383 patients with extranodal NK/T-cell lymphoma, nasal-type (ENKTCL) who were mostl...

    Si-Ye Chen, Yong Yang, Shu-Nan Qi, Ying Wang, Chen Hu, **a He, Li-Ling Zhang in Leukemia (2021)

  8. Article

    Open Access

    Genomic and transcriptomic landscapes of Epstein-Barr virus in extranodal natural killer T-cell lymphoma

    Extranodal natural killer T-cell lymphoma (nasal type; NKTCL) is an aggressive malignancy strongly associated with Epstein-Barr virus (EBV) infection. However, the role of EBV in NKTCL development is unclear, ...

    Rou-Jun Peng, Bo-Wei Han, Qing-Qing Cai, **ao-Yu Zuo, Tao **a, Jie-Rong Chen in Leukemia (2019)

  9. Article

    Open Access

    The effects of smoking and drinking on all-cause mortality in patients with dilated cardiomyopathy: a single-center cohort study

    Recent studies have shown that smoking and drinking are associated with poorer outcomes in patients with cardiomyopathy. The purpose of this study was to determine all-cause mortality in dilated cardiomyopathy...

    ** Li, Yang Liu, Rong Luo, Gang Li, Peng Luo in European Journal of Medical Research (2015)