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  1. Article

    Open Access

    Preparation of a Klebsiella pneumoniae conjugate nanovaccine using glycol-engineered Escherichia coli

    Engineered strains of Escherichia coli have been used to produce bioconjugate vaccines using Protein Glycan Coupling Technology (PGCT). Nanovaccines have also entered the vaccine development arena with advances i...

    Yan Liu, Chao Pan, Kangfeng Wang, Yan Guo, YanGe Sun, **ang Li in Microbial Cell Factories (2023)

  2. Article

    Open Access

    Manipulating the position of DNA expression cassettes using location tags fused to dCas9 (Cas9-Lag) to improve metabolic pathway efficiency

    Deactivated Cas9 (dCas9) led to significant improvement of CRISPR/Cas9-based techniques because it can be fused with a variety of functional groups to form diverse molecular devices, which can manipulate or mo...

    Qianwen **e, Siwei Li, Dongdong Zhao, Lijun Ye, Qingyan Li in Microbial Cell Factories (2020)

  3. Article

    Open Access

    Soft - sensing modeling based on ABC - MLSSVM inversion for marine low - temperature alkaline protease MP fermentation process

    Aiming at the characteristics of nonlinear, multi-parameter, strong coupling and difficulty in direct on-line measurement of key biological parameters of marine low-temperature protease fermentation process, a...

    Bo Wang, Meifang Yu, **anglin Zhu, Li Zhu in BMC Biotechnology (2020)