378 Result(s)
within
Li **a Han
Life Sciences
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Article
Open AccessSPARC overexpression in allogeneic adipose-derived mesenchymal stem cells in dog dry eye model induced by benzalkonium chloride
Nowadays, companion and working dogs hold significant social and economic importance. Dry eye, also known as dry keratoconjunctivitis (KCS), a common disease in ophthalmology, can readily impact a dog’s workin...
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Identification and characterization of four novel xiaomi alleles to facilitate foxtail millet as a C4 model plant
A diverse genetic background is essential for genetic analysis and functional genomics research in model plants. In this study, four novel xiaomi-like mutants in different genetic backgrounds, named xiaomi3, xiao...
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Open AccessiPSCs chondrogenic differentiation for personalized regenerative medicine: a literature review
Cartilage, an important connective tissue, provides structural support to other body tissues, and serves as a cushion against impacts throughout the body. Found at the end of the bones, cartilage decreases fri...
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Changes in above- and below-ground biodiversity mediate understory biomass response to prescribed burning in Northeast China
Biodiversity plays an important role in regulating understory biomass. Aboveground and belowground biodiversity changes in response to fire-induced changes in environmental factors. However, little is known ab...
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Open AccessSHH induces macrophage oxidative phosphorylation and efferocytosis to promote scar formation
Excessive scar formation such as hypertrophic scars and keloids, resulting from trauma or surgical procedures, present a widespread concern for causing disfigurement, discomfort, and functional limitations. Ma...
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Open AccessA chromosome-level genome assembly and annotation of the medicinal plant Lepidium apetalum
As a traditional Chinese medicine, Lepidium apetalum is commonly used for purging the lung, relieving dyspnea, alleviating edema, and has the significant pharmacological effects on cardiovascular disease, hyperli...
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Open AccessThe residual risk of inflammation and remnant cholesterol in acute coronary syndrome patients on statin treatment undergoing percutaneous coronary intervention
Residual risk assessment for acute coronary syndrome (ACS) patients after sufficient medical management remains challenging. The usefulness of measuring high-sensitivity C-reactive protein (hsCRP) and remnant ...
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Open AccessGasdermin D deficiency aborts myeloid calcium influx to drive granulopoiesis in lupus nephritis
Gasdermin D (GSDMD) is emerging as an important player in autoimmune diseases, but its exact role in lupus nephritis (LN) remains controversial. Here, we identified markedly elevated GSDMD in human and mouse L...
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Overexpression of TRIM44 mediates the NF-κB pathway to promote the progression of ovarian cancer
Ovarian cancer (OC) is the second most commonly seen cancer in the US, and patients with OC are commonly diagnosed in the advanced stage. Research into the molecular mechanisms and potential therapeutic target...
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Pan-evolutionary and regulatory genome architecture delineated by an integrated macro- and microsynteny approach
The forthcoming massive genome data generated by the Earth BioGenome Project will open up a new era of comparative genomics, for which genome synteny analysis provides an important framework. Profiling genome ...
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Enhanced therapeutic potential of Flotillins-modified MenSCs by improve the survival, proliferation and migration
Menstrual blood-derived endometrial stem cells (MenSCs) have attracted increasing interest due to their excellent safety, and lack of ethical dilemma as well as their ability to be periodically obtained in a n...
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Exogenous application of salicylic acid improves eradication of apple stem grooving virus and apple chlorotic leaf spot virus in apple
The presence of viral diseases poses a significant challenge to the high-quality, efficient, and sustainable production of apples. Virus eradication and the use of virus-free plants are currently the most cruc...
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Open AccessDrought response revealed by chromatin organization variation and transcriptional regulation in cotton
Cotton is a major world cash crop and an important source of natural fiber, oil, and protein. Drought stress is becoming a restrictive factor affecting cotton production. To facilitate the development of droug...
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Open AccessGrazing exclusion is more effective for vegetation restoration and nutrient transfer in the heavily degraded desert steppe
Grazing exclusion is an efficient practice to restore degraded grassland ecosystems by eliminating external disturbances and improving ecosystems’ self-healing capacities, which affects the ecological processe...
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Green manure substitution for potassium fertilizer promotes agro-ecosystem multifunctionality via triggering interactions among soil, plant and rhizosphere microbiome
Green manuring exhibits strong positive effects on soil fertility and crop yield, while its effects on agro-ecosystem multifunctionality (agro-EMF) and the underlying mechanisms are poorly understood.
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Open AccessDEC1 is involved in circadian rhythm disruption-exacerbated pulmonary fibrosis
The alveolar epithelial type II cell (AT2) and its senescence play a pivotal role in alveolar damage and pulmonary fibrosis. Cell circadian rhythm is strongly associated with cell senescence. Differentiated em...
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Open AccessTooth replacement in the early-diverging neornithischian Jeholosaurus shangyuanensis and implications for dental evolution and herbivorous adaptation in Ornithischia
Tooth replacement patterns of early-diverging ornithischians, which are important for understanding the evolution of the highly specialized dental systems in hadrosaurid and ceratopsid dinosaurs, are poorly kn...
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The impacts of planting patterns combined with irrigation management practices on soil water content, watermelon yield and quality
In arid and semi-arid regions of China, effective irrigation management and agronomic strategies are essential for enhancing the soil water environment and optimizing water productivity. A three-year (2020–202...
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Identifying strawberry appearance quality based on unsupervised deep learning
The strawberry appearance is an essential standard for judging the quality, so it is crucial to accurately identify the strawberry appearance quality for intelligent picking. This study proposed a new strawber...
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WOX2 functions redundantly with WOX1 and WOX4 to positively regulate seed germination in Arabidopsis
WOX family gene WOX2 is highly expressed during seed development, which functions redundantly with WOX1 and WOX4 to positively regulate seed germination.
