32 Result(s)

Article

Nab-paclitaxel plus platinum versus paclitaxel plus platinum as first-line therapy in patients with metastatic or recurrent cervical cancer

This study aimed to assess the efficacy and safety of nanoparticle albumin-bound paclitaxel (nab-paclitaxel) plus platinum versus paclitaxel plus platinum as first-line therapy in patients with metastatic or r...

Yuan Liu, Shan-shan Fang, Run-sheng Zhao… in Journal of Cancer Research and Clinical On… (2024)

Article

Effects of concurrent chemoradiotherapy with or without Endostar on the regression of retropharyngeal lymph node and prognosis of patients with locally advanced nasopharyngeal carcinoma: a retrospective study

To investigate the effect of combining Endostar with concurrent chemoradiotherapy (ECCRT) compared to concurrent chemoradiotherapy (CCRT) on the regression rate of retropharyngeal lymph nodes (RLNs) and the re...

Jun-Mei Song, Ning Mo, Yu-Qing Lv… in Journal of Cancer Research and Clinical On… (2024)

Article

A novel diagnostic model based on lncRNA PTPRE expression, neutrophil count and red blood cell distribution width for diagnosis of seronegative rheumatoid arthritis

Diagnosis of seronegative rheumatoid arthritis (SNRA) is difficult due to the lack of diagnostic markers. The study aims to construct a novel diagnostic model based on long noncoding RNAs (lncRNAs) expression ...

**fang **a, Huali Gao, Jifeng Tang, Renquan Jiang… in Clinical and Experimental Medicine (2024)

Article

An angiogenesis-associated gene-based signature predicting prognosis and immunotherapy efficacy of head and neck squamous cell carcinoma patients

To develop a model that can assist in the diagnosis and prediction of prognosis for head and neck squamous cell carcinoma (HNSCC).

Bangjie Chen, Yanxun Han, Shuyan Sheng… in Journal of Cancer Research and Clinical On… (2024)

Article

Deep learning algorithm-based multimodal MRI radiomics and pathomics data improve prediction of bone metastases in primary prostate cancer

Bone metastasis is a significant contributor to morbidity and mortality in advanced prostate cancer, and early diagnosis is challenging due to its insidious onset. The use of machine learning to obtain prognos...

Yun-Feng Zhang, Chuan Zhou, Sheng Guo… in Journal of Cancer Research and Clinical On… (2024)

Article

STING activation in TET2-mutated hematopoietic stem/progenitor cells contributes to the increased self-renewal and neoplastic transformation

Somatic loss-of-function mutations of the dioxygenase Ten-eleven translocation-2 (TET2) occur frequently in individuals with clonal hematopoiesis (CH) and acute myeloid leukemia (AML). These common hematopoiet...

Jiaying **e, Mengyao Sheng, Shaoqin Rong, Dan Zhou, Chao Wang, Wanling Wu… in Leukemia (2023)

Article

A nomogram incorporating Ki67 to predict survival of acral melanoma

The proliferation marker Ki67 is associated with the progression and prognosis of melanoma. However, its prognostic impact on acral melanoma (AM) remains unclear.

Yu Du, Caili Li, Lili Mao, **aoting Wei… in Journal of Cancer Research and Clinical On… (2023)

Article

Duodenal neuroendocrine neoplasms on enhanced CT: establishing a diagnostic model with duodenal gastrointestinal stromal tumors in the non-ampullary area and analyzing the value of predicting prognosis

To identify CT features and establish a diagnostic model for distinguishing non-ampullary duodenal neuroendocrine neoplasms (dNENs) from non-ampullary duodenal gastrointestinal stromal tumors (dGISTs) and to a...

Na Feng, Hai-Yan Chen, Yuan-Fei Lu, Yao Pan… in Journal of Cancer Research and Clinical On… (2023)

Article

MYD88^L265P and MYD88^other variants show different molecular characteristics and prognostic significance in diffuse large B-cell lymphoma

This study aims to investigate the clinical and molecular differences between diffuse large B-cell lymphoma (DLBCL) patients with MYD88^L265P and MYD88^other.

Yan Qin, Tian Qiu, Zucheng **e, **nrui Chen… in Journal of Cancer Research and Clinical On… (2023)

Article

Efficacy and safety of EGFR‑TKIs plus Shenqi Fuzheng injection for non-small cell lung cancer patients with EGFR-sensitive mutations

The aim of this retrospective study is to evaluate the impact on efficacy and safety between epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) alone and in combination with Shenqi Fuzheng...

Jia-li Wang, Chuan-sheng Chen, Zhi-rong Jia… in Journal of Cancer Research and Clinical On… (2023)

Article

Efficacy of avapritinib versus best available therapy in the treatment of advanced systemic mastocytosis

Advanced systemic mastocytosis (AdvSM) is a rare myeloid neoplasm associated with poor overall survival (OS). This study (NCT04695431) compared clinical outcomes between patients with AdvSM treated with avapri...

Andreas Reiter, Jason Gotlib, Iván Álvarez-Twose, Deepti H. Radia… in Leukemia (2022)

Article

Correction to: Expression profle of PU.1 in CD4⁺T cells from patients with systemic lupus erythematosus

A correction to this paper has been published: https://doi.org/10.1007/s10238-021-00731-x

Nan **ang, Xuan Fang, **ao-ge Sun, Ying-bo Zhou… in Clinical and Experimental Medicine (2022)

Article

FAM122A is required for hematopoietic stem cell function

Man-Hua Liu, **ao-Cui Zhang, **g Chen, Yun-Sheng Yang, Yin-Qi Wang… in Leukemia (2021)

Article

Comment on article by Christina Puhr Hannah et al.: Clinical characteristics and comparison of the outcome in young versus older patients with upper gastrointestinal carcinoma

**ao Yang, Chang-sheng **e in Journal of Cancer Research and Clinical Oncology (2021)

Article

Pyrvinium pamoate inhibits cell proliferation through ROS-mediated AKT-dependent signaling pathway in colorectal cancer

The use of the anthelmintic drug pyrvinium pamoate (PP) in cancer therapy has been extensively investigated in the last decade. PP has been shown to have an inhibitory effect in colorectal cancer (CRC), but th...

Wenqian Zheng, **hui Hu, Yiming Lv, Bingjun Bai, Lina Shan… in Medical Oncology (2021)

Article

Clinical characteristics of moderate and severe cases with COVID-19 in Wuhan, China: a retrospective study

With the outbreak of COVID-19 ongoing, this infectious disease has been posing a significant threat to public health. However, we are still relatively inexperienced on recognizing the clinical characteristics ...

Lingshuang Sheng, **ong Wang, Ning Tang, Fankai Meng… in Clinical and Experimental Medicine (2021)

Article

Validation of nomogram-revised risk index and comparison with other models for extranodal nasal-type NK/T-cell lymphoma in the modern chemotherapy era: indication for prognostication and clinical decision-making

Derived from our original nomogram study by using the risk variables from multivariable analyses in the derivation cohort of 1383 patients with extranodal NK/T-cell lymphoma, nasal-type (ENKTCL) who were mostl...

Si-Ye Chen, Yong Yang, Shu-Nan Qi, Ying Wang, Chen Hu, **a He, Li-Ling Zhang… in Leukemia (2021)

Article

COVID-19 in persons with chronic myeloid leukaemia

We studied by questionnaire 530 subjects with chronic myeloid leukaemia (CML) in Hubei Province during the recent SARS-CoV-2 epidemic. Five developed confirmed (N = 4) or probable COVID-19 (N = 1). Prevalence of ...

Weiming Li, Danyu Wang, **gming Guo, Guolin Yuan, Zhuangzhi Yang… in Leukemia (2020)

Article

S100A9-induced overexpression of PD-1/PD-L1 contributes to ineffective hematopoiesis in myelodysplastic syndromes

Myelodysplastic syndromes (MDS) are characterized by dysplastic and ineffective hematopoiesis that can result from aberrant expansion and activation of myeloid-derived suppressor cells (MDSCs) within the bone ...

Pinyang Cheng, Erika A. Eksioglu, **anghong Chen, Wendy Kandell, Thu Le Trinh… in Leukemia (2019)

Article

Genomic and transcriptomic landscapes of Epstein-Barr virus in extranodal natural killer T-cell lymphoma

Extranodal natural killer T-cell lymphoma (nasal type; NKTCL) is an aggressive malignancy strongly associated with Epstein-Barr virus (EBV) infection. However, the role of EBV in NKTCL development is unclear, ...

Rou-Jun Peng, Bo-Wei Han, Qing-Qing Cai, **ao-Yu Zuo, Tao **a, Jie-Rong Chen… in Leukemia (2019)