109 Result(s)

Article

Sentinel lymph node biopsies in breast cancer

A Hess, MO Flüβ, C Nestle-Krämling, HG Bender, P Dall in Breast Cancer Research (2001)

Article

Relationship between cyclooxygenase 8473T>Cpolymorphism and the risk of lung cancer: a case-control study

Cyclooxygenase-2 (COX-2) plays an important role in the development of lung cancer. DNA sequence variations in the COX-2 gene may lead to altered COX-2 production and/or activity, and so they cause inter-individu...

Jung Min Park, ** Eun Choi, Myung Hwa Chae, Won Kee Lee, Sung Ick Cha… in BMC Cancer (2006)

Article

Polymorphisms in the epidermal growth factor receptor gene and the risk of primary lung cancer: a case-control study

Polymorphisms in Epidermal Growth Factor Receptor (EGFR) gene may influence EGFR production and/or activity, thereby modulating susceptibility to lung cancer. To test this hypothesis, we investigated the associat...

** Eun Choi, Sun Ha Park, Kyung Mee Kim, Won Kee Lee, Sin Kam, Sung Ick Cha… in BMC Cancer (2007)

Article

Vav3 oncogene activates estrogen receptor and its overexpression may be involved in human breast cancer

Our previous study revealed that Vav3 oncogene is overexpressed in human prostate cancer, activates androgen receptor, and stimulates growth in prostate cancer cells. The current study is to determine a potent...

Kiwon Lee, Yin Liu, Jun Qin Mo, **song Zhang, Zhongyun Dong, Shan Lu in BMC Cancer (2008)

Article

Systematic validation of predicted microRNAs for cyclin D1

MicroRNAs are the endogenous small non-coding RNA molecules capable of silencing protein coding genes at the posttranscriptional level. Based on computer-aided predictions, a single microRNA could have over a ...

Qiong Jiang, Ming-Guang Feng, Yin-Yuan Mo in BMC Cancer (2009)

Article

The investigation of Mitogen-Activated Protein kinase Phosphatase-1 as a potential pharmacological target in non-small cell lung carcinomas, assisted by non-invasive molecular imaging

Invasiveness and metastasis are the most common characteristics of non small cell lung cancer (NSCLC) and causes of tumour-related morbidity and mortality. Mitogen-activated protein kinases (MAPKs) signalling ...

Cheng-Jeng Tai, Alexander TH Wu, Jeng-Feng Chiou, Hsun-** Jan, Hon-Jian Wei… in BMC Cancer (2010)

Article

TFPI-2 is a putative tumor suppressor gene frequently inactivated by promoter hypermethylation in nasopharyngeal carcinoma

Epigenetic silencing of tumor suppressor genes play important roles in NPC tumorgenesis. Tissue factor pathway inhibitor-2 (TFPI-2), is a protease inhibitor. Recently, TFPI-2 was suggested to be a tumor suppresso...

Shumin Wang, Xue **ao, **aoying Zhou, Tingting Huang, Chun** Du, Nana Yu… in BMC Cancer (2010)

Article

The CpG island methylator phenotype may confer a survival benefit in patients with stage II or III colorectal carcinomas receiving fluoropyrimidine-based adjuvant chemotherapy

Colorectal carcinoma (CRC) with CpG island methylator phenotype (CIMP) is recognized as a distinct subgroup of CRC, and CIMP status affects prognosis and response to chemotherapy. Identification of CIMP status...

Byung-Hoon Min, Jeong Mo Bae, Eui ** Lee, Hong Suk Yu, Young-Ho Kim… in BMC Cancer (2011)

Article

Expression and clinical significance of extracellular matrix protein 1 and vascular endothelial growth factor-C in lymphatic metastasis of human breast cancer

Extracellular matrix protein 1 (ECM1) and vascular endothelial growth factor-C (VEGF-C) are secretory glycoproteins that are associated with lymphangiogenesis; these proteins could, therefore, play important r...

Qiu-Wan Wu, Hong-Qiang She, **g Liang, Yu-Fan Huang, Qing-Mo Yang… in BMC Cancer (2012)

Article

Conspicuity of breast lesions at different b values on diffusion-weighted imaging

Diffusion-weighted (DW) imaging has shown potential to differentiate between malignant and benign breast lesions. However, different b values have been used with varied sensitivity and specificity. This study ...

**n Chen, **-**g He, Rui **, You-Min Guo, **an Zhao, Hua-Feng Kang… in BMC Cancer (2012)

Article

Low BRMS1 expression promotes nasopharyngeal carcinoma metastasis in vitro and in vivo and is associated with poor patient survival

Breast cancer metastasis suppressor 1 (BRMS1) is a metastasis suppressor gene. This study aimed to investigate the impact of BRMS1 on metastasis in nasopharyngeal carcinoma (NPC) and to evaluate the prognostic...

Rui-Xue Cui, Na Liu, Qing-Mei He, Wen-Fei Li, Bi-Jun Huang, Ying Sun… in BMC Cancer (2012)

Article

Assessment of the dynamic range in dynamic contrast-enhanced magnetic resonance imaging breast examinations

AEW Ledger, M Borri, M Schmidt, R Pope, E Scurr, T Wallace… in Breast Cancer Research (2012)

Article

The role of brevican in glioma: promoting tumor cell motility in vitro and in vivo

Malignant glioma is a common primary tumor of the central nervous system. Brevican, an abundant extracellular matrix component in the adult brain, plays a critical role in the process of glioma. The mechanisms...

Renquan Lu, Chengsheng Wu, Lin Guo, Yingchao Liu, Wei Mo, Huijie Wang… in BMC Cancer (2012)

Article

Various types of intracorporeal esophagojejunostomy after laparoscopic total gastrectomy for gastric cancer

Even for expert surgeons, esophagojejunostomy after laparoscopic total gastrectomy (LTG) is not always easy to perform. Herein, we compare various types of esophagojejunostomy in terms of the technical aspects...

Jung Ho Shim, Han Mo Yoo, Seong Il Oh, Myung ** Nam, Hae Myung Jeon… in Gastric Cancer (2013)

Article

GPR30 as an initiator of tamoxifen resistance in hormone-dependent breast cancer

Tamoxifen is widely used to treat hormone-dependent breast cancer, but its therapeutic benefit is limited by the development of drug resistance. Here, we investigated the role of estrogen G-protein coupled rec...

Zhiqiang Mo, Manran Liu, Fangfang Yang, Haojun Luo, Zhenhua Li… in Breast Cancer Research (2013)

Article

Erratum to: CCR7 and VEGF-C: Molecular Indicator of Lymphatic Metastatic Recurrence in pN0 Esophageal Squamous Cell Carcinoma after Ivor-Lewis Esophagectomy?

Yong Ming Song MM, Zhou Wang MD, **ang Yan Liu MD… in Annals of Surgical Oncology (2013)

Article

Macrophage inhibitory cytokine 1 (MIC-1/GDF15) as a novel diagnostic serum biomarker in pancreatic ductal adenocarcinoma

Macrophage inhibitory cytokine 1 (MIC-1/GDF15) has been identified as a potential novel biomarker for detection of pancreatic cancer (PCa). However, the diagnostic value of serum MIC-1 for pancreatic ductal ad...

**aobing Wang, Yanfen Li, Haimei Tian, Jun Qi, Mo Li, Chao Fu, Fan Wu… in BMC Cancer (2014)

Article

A new T classification based on masticator space involvement in nasopharyngeal carcinoma: a study of 742 cases with magnetic resonance imaging

The aim of this study was to investigate the prognostic significance and various classifications for anatomic masticator space involvement (MSI) in patients with nasopharyngeal carcinoma (NPC).

Dong-Hua Luo, **g Yang, Hui-Zhi Qiu, Ting Shen, Qiu-Yan Chen, Pei-Yu Huang… in BMC Cancer (2014)

Article

Nasopharyngeal carcinoma with paranasal sinus invasion: the prognostic significance and the evidence-based study basis of its T-staging category according to the AJCC staging system

To evaluate the prognostic significance of paranasal sinus invasion for patients with NPC and to provide empirical proofs for the T-staging category of paranasal sinus invasion according to the AJCC staging sy...

Li Tian, Yi-Zhuo Li, Yun-**an Mo, Li-Zhi Liu, Chuan-Miao **e, Xue-**a Liang… in BMC Cancer (2014)

Article

Phase I/II study of temsirolimus for patients with unresectable Hepatocellular Carcinoma (HCC)- a correlative study to explore potential biomarkers for response

The oncogenic PI3K/Akt/mTOR pathway is frequently activated in HCC. Data on the mTOR inhibitor, temsirolimus, is limited in HCC patients with concomitant chronic liver disease. The objectives of this study wer...

Winnie Yeo, Stephen L Chan, Frankie KF Mo, Cheuk M Chu, Joyce WY Hui… in BMC Cancer (2015)