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Article
Association between Copper Exposure and Cognitive Function: A Cross-Sectional Study in a County, Guangxi, China
There has been growing attention to the impact of copper exposure on cognitive function; however, current research on the specific information regarding urinary copper and cognitive function is limited, partic...
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Article
Open AccessCrosstalk among proximal tubular cells, macrophages, and fibroblasts in acute kidney injury: single-cell profiling from the perspective of ferroptosis
The link between ferroptosis, a form of cell death mediated by iron and acute kidney injury (AKI) is recently gaining widespread attention. However, the mechanism of the crosstalk between cells in the pathogen...
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Article
Correction to: Efects of Manganese and Iron, Alone or in Combination, on Apoptosis in BV2 Cells
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Article
Effects of Manganese and Iron, Alone or in Combination, on Apoptosis in BV2 Cells
The aim of study was to address the effects of manganese and iron, alone and in combination, on apoptosis of BV2 microglia cells, and to determine if combined exposure to these metals augments their individual...
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Article
The Association Between Dietary Magnesium Intake and Pulmonary Function: Recent Fndings from NHANES 2007–2012
This article aims to study the correlation between dietary magnesium intake and pulmonary function, utilizing data from the National Health and Nutrition Examination Survey (NHANES) database. This cross-sectio...
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Article
The Association between Magnesium Depletion Score and Hypertension in US Adults: Evidence from the National Health and Nutrition Examination Survey (2007–2018)
The magnesium depletion score (MDS) emerges as a new valuable predictor of the body’s magnesium status index. This study aims to explore the link between MDS and hypertension (HTN) using the National Health an...
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Article
Association Between Combined Polymetallic Exposure and Osteoporosis
Combined polymetallic exposure may be an influential factor in osteoporosis. This study aimed to explore the association between polymetallic combined exposure and osteoporosis. A total of 2115 participants we...
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Article
Open AccessThyroglobulin as a Sensitive Biomarker of Iodine Status in Mildly and Moderately Iodine-Deficient Pregnant Women
Pregnant women are more susceptible to iodine deficiency. However, there are limitations in existing indicators for the evaluation of iodine nutrition in pregnant women. The study aimed to explore whether thyr...
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Article
Association of CYP19A1 Gene, Plasma Zinc, and Urinary Zinc with the Risk of Type 2 Diabetes Mellitus in a Chinese Population
To explore the effects of CYP19A1 gene polymorphisms, plasma zinc, and urinary zinc levels and their interactions on type 2 diabetes mellitus (T2DM) in residents of Gongcheng County, Guangxi, China. The case–c...
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Article
Effects of Molybdenosis on Antioxidant Capacity in Endangered Przewalski’s Gazelles in the Qinghai Lake National Nature Reserve in the Northwestern China
The purpose of this study is to investigate the effects of molybdenosis on antioxidant capacity in endangered Przewalski’s gazelles (Procapra przewalskii) in the animal rescue center in the Qinghai Lake National ...
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Article
Associations of Dietary and Plasma Copper Levels with Liver Function in a Chinese Population
The potential mechanisms underlying the association between copper (Cu) exposure and impaired liver function are unclear. This study aimed to investigate the potential associations of dietary Cu intake and pla...
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Article
JAK2/STAT3 Signaling Pathway and Klotho Gene in Cadmium-induced Neurotoxicity In Vitro and In Vivo
Cadmium (Cd), a common heavy metal in the environment, is associated with cognitive impairment. In the present study, we carried out a preliminary inquiry to explore whether Cd causes neurotoxicity by regulati...
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Article
Sex-Specific Associations of Urinary Metals with Renal Function: a Cross-sectional Study in China
Extensive studies have revealed the link between heavy metals and CKD. Compared to single meta-elements, mixture of metals reflect real-life metals exposure scenarios and are of interest. However, the mechanis...
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Article
Correction to: Systematic single-cell dissecting reveals heterogeneous oncofetal reprogramming in the tumor microenvironment of gastric cancer
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Article
Systematic single-cell dissecting reveals heterogeneous oncofetal reprogramming in the tumor microenvironment of gastric cancer
Oncofetal reprogramming of the tumor microenvironment is clinically relevant. This study used the non-negative matrix factorial (NMF) algorithm for single-cell RNA sequencing data of gastric cancer (GC) based ...
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Article
Association of Dietary and Plasma Magnesium with Glycaemic Markers in a Chinese Population
Certain metals play a role in the pathogenesis of diabetes. This study aimed to investigate the potential association of plasma magnesium (Mg) and dietary intake of Mg with glycaemic markers. A cross-sectional...
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Article
Correction to: Gpx4, Selenov, and Txnrd3 Are Three Most Testis-Abundant Selenogenes Resistant to Dietary Selenium Concentrations and Actively Expressed During Reproductive Ages in Rats
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Article
Gpx4, Selenov, and Txnrd3 Are Three Most Testis-Abundant Selenogenes Resistant to Dietary Selenium Concentrations and Actively Expressed During Reproductive Ages in Rats
Almost all selenogenes are expressed in the testis, and those have the highest and constant expressions will be the primary candidates for functional analysis of selenium (Se) in male reproduction. This study ...
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Article
Hedgehog pathway is negatively regulated during the development of Drosophila melanogaster PheRS-m (Drosophila homologs gene of human FARS2) mutants
Hereditary spastic paraplegia (HSP) is a neurodegeneration disease, one of the reasons is caused by autosomal recessive missense mutation of the karyogene that encodes phenylalanyl-tRNA synthetase 2, mitochond...
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Article
Associations Between Plasma Metals and Cognitive Function in People Aged 60 and Above
The objective of the study was to explore the relationship between the plasma levels of 22 metals and cognition status in older adults aged 60 years and above. A cross-sectional survey was conducted between 20...