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    Article

    Dynamic interplay between enhancer–promoter topology and gene activity

    A long-standing question in gene regulation is how remote enhancers communicate with their target promoters, and specifically how chromatin topology dynamically relates to gene activation. Here, we combine gen...

    Hongtao Chen, Michal Levo, Lev Barinov, Miki Fujioka, James B. Jaynes in Nature Genetics (2018)

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    Article

    Improving the Efficacy of ACR TI-RADS Through Deep Learning-Based Descriptor Augmentation

    Thyroid nodules occur in up to 68% of people, 95% of which are benign. Of the 5% of malignant nodules, many would not result in symptoms or death, yet 600,000 FNAs are still performed annually, with a PPV of 5...

    Lev Barinov, Ajit Jairaj, William D. Middleton, Michael D. in Journal of Digital Imaging (2023)