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  1. No Access

    Article

    Base-pair-resolution genome-wide map** of active RNA polymerases using precision nuclear run-on (PRO-seq)

    Mahat et al. describe how to map the genome-wide positions of active RNA polymerases using a modified nuclear run-on approach called PRO-seq. Details for PRO-cap, a modification that identifies transcription star...

    Dig Bijay Mahat, Hojoong Kwak, Gregory T Booth, Iris H Jonkers… in Nature Protocols (2016)

  2. No Access

    Article

    Identification of active transcriptional regulatory elements from GRO-seq data

    Using data from global run-on and sequencing (GRO-seq) or related methods, the dREG software identifies a new class of transcriptional regulatory elements with strong evidence for directing active transcription.

    Charles G Danko, Stephanie L Hyland, Leighton J Core, Andre L Martins… in Nature Methods (2015)