Skip to main content

2 Result(s)

within Leighton J Core Remove this filter English Remove this filter Agriculture Remove this filter Cancer Research Remove this filter

and

  1. No Access

    Article

    Analysis of nascent RNA identifies a unified architecture of initiation regions at mammalian promoters and enhancers

    John Lis, Adam Siepel and colleagues map transcription start sites across the genome in two human cell lines using a nuclear run-on protocol called GRO-cap. They find a common architecture of initiation at bot...

    Leighton J Core, André L Martins, Charles G Danko, Colin T Waters… in Nature Genetics (2014)

  2. No Access

    Article

    Chromatin run-on and sequencing maps the transcriptional regulatory landscape of glioblastoma multiforme

    The human genome encodes a variety of poorly understood RNA species that remain challenging to identify using existing genomic tools. We developed chromatin run-on and sequencing (ChRO-seq) to map the location...

    Tinyi Chu, Edward J. Rice, Gregory T. Booth, H. Hans Salamanca… in Nature Genetics (2018)