10,090 Result(s)
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Le**g Wang
Biomedicine
Neurosciences
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Article
Amphetamine toxicity in isolated and aggregated mice
The phenomenon of increased amphetamine toxicity in aggregated mice was studied by placing one mouse treated with amphetamine among either 9 untreated (1 A+9 U) or 9 sedated (1 A+9 S) mice. Mortalities were recor...
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Article
Characteristics of pentazocine dependence in hospitalized patients after naloxone administration
In a double blind study, saline and a narcotic antagonist, naloxone, were given on separate days to 8 patients who had been receiving parenteral pentazocine daily for at least one month. The abstinence score f...
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Article
Platelet adenylate cyclase responses in depression: Implications for a receptor defect
The dose-dependent stimulatory response of prostaglandin E1 (PGE1) on the net synthesis of 3H-adenosine 3′,5′-monophosphate (cyclic AMP) in platelets whose adenine nucleotide pools had been labelled by prior incu...
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Article
The activity of respiratory neurons before and during panting in the cat
The effects of heating the preoptic/anterior hypothalamic (PO/AH) region on medullary respiratory neurons were studied in urethane-anesthetized, spontaneously breathing cats. The efferent phrenic nerve dischar...
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Chapter
The Influence of Serotonin on Seizure Susceptibility in the Gerbil
5-hydroxytryptophan (5-HTP) (50 mg/kg, I.P.) increased central serotonin (5-HT) levels and delayed the onset of seizure during reflow in gerbils subjected to transient bilateral blockade with dimethyl tryptami...
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Chapter
Reemphasis of the Role of 5-Hydroxytryptamine in Cerebral Ischemia
Cortical monoamine changes during ischemic episodes of up to one hour were studied in the gerbil. Norepinephrine (NE) levels decreased after 60 minutes in the occluded hemisphere of animals with stroke, but do...
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Article
Reserpine and alpha-methyldopa in the treatment of tardive dyskinesia
Thirty inpatients with evidence of tardive dyskinesia secondary to antipsychotic medications participated in this double-blind, controlled, randomized study comparing reserpine, α-methyldopa and placebo. Reser...
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Article
Propoxyphene napsylate compared to methadone for opiate dependence
When high single doses of propoxyphene napsylate (PN) were given to patients on a methadone maintenance program, results indicated that, to avoid undesirable side effects, the dose should not exceed 600 mg. Ho...
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Article
Effect of luminal glucose on cell membrane potential and sodium electrochemical gradient in the absence and presence of ouabain
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Article
cAMP hyperolarizes the cell membrane potential and decreases intracellular Na+ activity in frog proximal tubule
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Article
Effects of inhibition of chloride transport on intracellular sodium activity in distal Amphibian nephron
Previous experiments had demonstrated that cell chloride activities in early distal tubule cells of Amphiuma are above equilibrium distribution. Chloride activities fell sharply towards electrochemical equilib...
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Chapter
Chemical Studies on the Porcine Myelin Basic Protein
An encephalitogenic myelin basic protein was isolated from fresh frozen pig brains by acid- acetone extraction and purified to homogeneity by CM-ceilulose column chromatography and gelfiltration on a Sephacryl...
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Article
Intercellular junctions in the human fetal membranes
Freeze-fracture replicas of the human reflected and placental amnion and chorion laeve at term were studied in order to give a systematic survey of the nature and extension of the intercellular junctions in th...
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Article
Effect of luminal potassium on cellular sodium activity in the early distal tubule ofAmphiuma kidney
From previous studies it is known that a furosemide-sensitive sodium chloride cotransport system is operative in the luminal cell membrane of the early distal amphibian tubule. Since inhibition of sodium chlor...
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Article
The effect of cAMP on the cell membrane potential and intracellular ion activities in proximal tubule ofRana esculenta
Experiments were performed in proximal tubule of the isolated perfused frog kidney to evaluate peritubular cell membrane potentials (PDpt), and the intracellular ion activities of sodium (Nai ü), chloride (Cli −)...
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Article
Binocular responses of cortical cells and the callosal projection in the albino rat
Four hundred and fifteen cells were recorded in the binocular segment of the visual cortex in the albino rat. Cells encountered were mainly dominated by the contralateral eye. The percentage of binocularly-dri...
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Article
Representation of the binocular visual field in the superior colliculus of the albino rat
Electrophysiological map** techniques were used to determine the representation of the central field of vision in the superior colliculus of the albino rat. The retinotopic map for the contralateral eye is s...
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Article
Evidence for an amiloride sensitive Na+ pathway in the amphibian diluting segment induced by K+ adaptation
The effect of amiloride on cell membrane potentials and intracellular Na activity (Nai) was tested in early distal tubules of the isolated perfused kidney of control and of K-adapted (high-K diet)Amphiuma. Conven...
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Article
The effect of ouabain on intracellular activities of K+, Na+, Cl−, H+ and Ca2+ in proximal tubules of frog kidneys
Using conventional and ion selective microelectrodes, the effect of ouabain (10−4 mol/l) on peritubular cell membrane potential (PDpt), on intracellular pH (pHi) as well as on the intracellular ion activities of ...
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Article
The influence of intracellular sodium activity on the transport of glucose in proximal tubule of frog kidney
Inhibition of basolateral Na+/K+ ATPase by ouabain eventually abolishes transport of glucose. The present study was performed to test, if this effect is due to a dissipation of the electrochemical gradient for so...
