Skip to main content

1 Result(s)

within Lauren R. Hammond Remove this filter Science, Humanities and Social Sciences, multidisciplinary Remove this filter

and

  1. Article

    Open Access

    A unique class of Zn2+-binding serine-based PBPs underlies cephalosporin resistance and sporogenesis in Clostridioides difficile

    Treatment with β-lactam antibiotics, particularly cephalosporins, is a major risk factor for Clostridioides difficile infection. These broad-spectrum antibiotics irreversibly inhibit penicillin-binding proteins (...

    Michael D. Sacco, Shaohui Wang, Swamy R. Adapa, **ujun Zhang… in Nature Communications (2022)

    Download PDF (2667 KB) View Article