9 Result(s)
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Article
Open AccessRelational continuity may give better clinical outcomes in patients with serious mental illness – a systematic review
Continuity of care is considered important for results of treatment of serious mental illness (SMI). Yet, evidence of associations between relational continuity and different medical and social outcomes is spa...
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Article
Open AccessMap** the expression of an ANK3 isoform associated with bipolar disorder in the human brain
The gene ankyrin-3 (ANK3) has been consistently associated with bipolar disorder (BD) in several genome-wide association studies (GWAS). The exact molecular mechanisms underlying this genetic association remain u...
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Article
Open AccessExploring lithium’s transcriptional mechanisms of action in bipolar disorder: a multi-step study
Lithium has been the first-line treatment for bipolar disorder (BD) for more than six decades. Although the molecular effects of lithium have been studied extensively and gene expression changes are generally ...
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Article
Open AccessA Qualitative Study of Caregivers’ Experiences, Motivation and Challenges Using a Web-Based Mindfulness Intervention
Caregivers report experiences of stress and burden that can affect their health negatively. Web-based mindfulness interventions have shown beneficial health effects in clinical and non-clinical populations, in...
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Open AccessElevated expression of a minor isoform of ANK3 is a risk factor for bipolar disorder
Ankyrin-3 (ANK3) is one of the few genes that have been consistently identified as associated with bipolar disorder by multiple genome-wide association studies. However, the exact molecular basis of the associati...
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Open AccessThe effectiveness of narrative enhancement and cognitive therapy: a randomized controlled study of a self-stigma intervention
Stigma has been proposed to be one of the most serious obstacles to successful treatment, rehabilitation and inclusion in society of people with severe mental illness. An aspect of stigma which has been increa...
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Open AccessThe effectiveness of an anti-stigma intervention in a basic police officer training programme: a controlled study
Stigma and discrimination are still prominent features of the life situation of persons with mental illness, adding to the burden of the illness, causing a lowered self-esteem, quality of life and affecting po...
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Open AccessOvercoming recruitment barriers revealed high readiness to participate and low dropout rate among people with schizophrenia in a randomized controlled trial testing the effect of a Guided Self-Determination intervention
Recruitment is one of the most serious challenges in performing randomized controlled trials. Often clinical trials with participants diagnosed with schizophrenia are terminated prematurely because of recruitm...
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Open AccessTest - retest reliability of two instruments for measuring public attitudes towards persons with mental illness
Research has identified stigmatization as a major threat to successful treatment of individuals with mental illness. As a consequence several anti-stigma campaigns have been carried out. The results have been ...
