4 Result(s)

Article

Exploiting the fibroblast growth factor receptor-1 vulnerability to therapeutically restrict the MYC-EZH2-CDKN1C axis-driven proliferation in Mantle cell lymphoma

Mantle cell lymphoma (MCL) is a lethal hematological malignancy with a median survival of 4 years. Its lethality is mainly attributed to a limited understanding of clinical tumor progression and resistance to ...

Anuvrat Sircar, Satishkumar Singh, Zijun Y. Xu-Monette, Krysta Mila Coyle… in Leukemia (2023)

Article

Dnmt1 links BCR-ABLp210 to epigenetic tumor stem cell priming in myeloid leukemia

Carolina Vicente-Dueñas, Inés González-Herrero, Lalit Sehgal… in Leukemia (2019)

Article

LncRNA MALAT1 promotes development of mantle cell lymphoma by associating with EZH2

Mantle cell lymphoma (MCL) is considered an aggressive subtype of non-Hodgkin’s lymphoma with variable treatment responses. There is an urgent need to identify novel markers with prognostic and therapeutic val...

**n Wang, Lalit Sehgal, Neeraj Jain, Tamer Khashab… in Journal of Translational Medicine (2016)

Article

Fascin overexpression promotes neoplastic progression in oral squamous cell carcinoma

Fascin is a globular actin cross-linking protein, which plays a major role in forming parallel actin bundles in cell protrusions and is found to be associated with tumor cell invasion and metastasis in various...

Hunain Alam, Amruta V Bhate, Prakash Gangadaran, Sharda S Sawant… in BMC Cancer (2012)