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  1. Article

    Open Access

    Biological significance of FoxN1 gain-of-function mutations during T and B lymphopoiesis in juvenile mice

    FoxN1 is cell-autonomously expressed in skin and thymic epithelial cells (TECs), essential for their development. Inborn mutation of FoxN1 results in hair follicle and TEC development failure, whereas insufficien...

    L Ruan, Z Zhang, L Mu, P Burnley, L Wang, B Coder, Q Zhuge, D-M Su in Cell Death & Disease (2014)

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  2. Article

    Open Access

    Targeting heat-shock protein 90 with ganetespib for molecularly targeted therapy of gastric cancer

    Gastric cancer (GC) remains the fifth most common cancer worldwide. Heat-shock protein 90 (HSP90) has become an attractive therapeutic target in treating cancers, because of its abnormally high expression in c...

    H Liu, J Lu, Y Hua, P Zhang, Z Liang, L Ruan, C Lian, H Shi, K Chen… in Cell Death & Disease (2015)

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