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  1. No Access

    Article

    Potential intake of phytosterols/-stanols: results of a simulation study

    Background: Different doses of phytosterols/-stanols up to a maximum of 4.0 g/day have been used in human safety studies, whereas only one small-scale study investigated some detailed clinical information about c...

    N De Jong, L Pijpers, J K Bleeker, M C Ocké in European Journal of Clinical Nutrition (2004)

  2. No Access

    Article

    The disposition of valproate and its metabolites in the late first trimester and early second trimester of pregnancy in maternal serum, urine, and amniotic fluid: Effect of dose, co-medication, and the presence of spina bifida

    We have studied 52 pregnancies in epileptic women taking long-term valproate and have measured the concentrations of the parent compound and 13 of its metabolites by gas chromatography-mass spectrometry in amn...

    J. G. C. Omtzigt, H. Nau, F. J. Los… in European Journal of Clinical Pharmacology (1992)