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Open AccessCorrection: Exosomal Wnt-induced dedifferentiation of colorectal cancer cells contributes to chemotherapy resistance
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Adipose insulin resistance is associated with cardiovascular risk factors in polycystic ovary syndrome
The effects of adipose insulin resistance on cardiovascular risk factors in polycystic ovary syndrome (PCOS) remain largely unknown. We aimed to investigate associations between adipose insulin resistance and ...
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Article
Open AccessExosomal Wnt-induced dedifferentiation of colorectal cancer cells contributes to chemotherapy resistance
Cancer stem cells (CSCs) are inherently resistant to chemotherapy, and CSCs in chemotherapy-failed recurrent tumors are enriched; however, the cellular origin of chemotherapy-induced CSC enrichment remains unc...
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Article
An EGFR/PI3K/AKT axis promotes accumulation of the Rac1-GEF Tiam1 that is critical in EGFR-driven tumorigenesis
Epidermal growth factor receptor (EGFR) signaling regulates cell growth and survival, and its overactivation drives cancer development. One important branch of EGFR signaling is through activation of GTPase Ra...
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Prevalence and predictors of resistance and aerobic exercise among hypertensive adults in the United States