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    Age-associated changes in interferon-γ and interleukin-4 secretion by purified human CD4+ and CD8+ T cells

    Aging is associated with a decline in immune function. Interferon-γ (IFN-γ) and interleukin-4 (IL-4), two important immune deviation-related cytokines, are mainly produced by type 1 and type 2 T cells, respect...

    Chung-Jen Yen, Shuei-Liong Lin, Kuo-Tong Huang… in Journal of Biomedical Science (2000)