19 Result(s)
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Article
Open AccessA comparative study of interfacial thermal conductance between metal and semiconductor
To understand and control thermal conductance of interface between metal and semiconductor has now become a crucial task for the thermal design and management of nano-electronic and micro-electronic devices. T...
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Open AccessCadherin repeat 5 mutation associated with Bt resistance in a field-derived strain of pink bollworm
Evolution of resistance by pests reduces the benefits of transgenic crops that produce insecticidal proteins from Bacillus thuringiensis (Bt). Here we analyzed resistance to Bt toxin Cry1Ac in a field-derived str...
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Article
Open AccessFundc1 is necessary for proper body axis formation during embryogenesis in zebrafish
FUN14 domain-containing protein 1 (FUNDC1) is a mitochondrial outer membrane protein which is responsible for hypoxia-induced mitophagy in mammalian cells. Knockdown of fundc1 is known to cause severe defects in ...
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Open AccessThree-dimensional open nano-netcage electrocatalysts for efficient pH-universal overall water splitting
High-efficiency water electrolysis is the key to sustainable energy. Here we report a highly active and durable RuIrOx (x ≥ 0) nano-netcage catalyst formed during electrochemical testing by in-situ etching to rem...
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Open AccessRegulating the coordination structure of single-atom Fe-NxCy catalytic sites for benzene oxidation
Atomically dispersed metal-N-C structures are efficient active sites for catalyzing benzene oxidation reaction (BOR). However, the roles of N and C atoms are still unclear. We report a polymerization-regulated...
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Open AccessTransposon insertion causes cadherin mis-splicing and confers resistance to Bt cotton in pink bollworm from China
Transgenic crops producing insecticidal proteins from Bacillus thuringiensis (Bt) are cultivated extensively, but rapid evolution of resistance by pests reduces their efficacy. We report a 3,370-bp insertion in a...
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Open AccessHuman-Pathogenic Enterocytozoon bieneusi in Captive Giant Pandas (Ailuropoda melanoleuca) in China
Human and animal infections of Enterocytozoon bieneusi (E. bieneusi) have consistently been reported worldwide, garnering public attention; however, the molecular epidemiology of E. bieneusi in the giant panda re...
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Open AccessDACH1 suppresses breast cancer as a negative regulator of CD44
Dachshund homolog 1 (DACH1), a key cell fate determination factor, contributes to tumorigenesis, invasion, metastasis of human breast neoplasm. However, the exact molecular mechanisms for the anti-tumor roles ...
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Open AccessCharacterization of the natural enemy community attacking cotton aphid in the Bt cotton ecosystem in Northern China
Planting Bt cotton in China since 1997 has led to important changes in the natural enemy communities occurring in cotton, however their specific effect on suppressing the cotton aphids (being notorious in conv...
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Open AccessAPN1 is a functional receptor of Cry1Ac but not Cry2Ab in Helicoverpa zea
Lepidopteran midgut aminopeptidases N (APNs) are phylogenetically divided into eight clusters, designated as APN1–8. Although APN1 has been implicated as one of the receptors for Cry1Ac in several species, its...
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Open AccessVolatile fragrances associated with flowers mediate host plant alternation of a polyphagous mirid bug
Apolygus lucorum (Hemiptera: Miridae) is an important insect pest of cotton and fruit trees in China. The adults prefer host plants at the flowering stage and their populations track flowering plants both spatial...
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Open AccessThe inhibitory effects of AR/miR-190a/YB-1 negative feedback loop on prostate cancer and underlying mechanism
Prostate cancer at advanced stages including metastatic and castration-resistant cancer remains incurable due to the lack of effective therapies. MiR-190a belongs to the small noncoding RNA family and has an i...
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Article
Open AccessMeta-analysis reveals the correlation of Notch signaling with non-small cell lung cancer progression and prognosis
Various studies have assessed the clinicopathological and prognostic value of Notch1 and Notch3 expression in Non-small cell lung cancer (NSCLC), but their results remain controversial. This meta-analysis was ...
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Open AccessCross-resistance and interactions between Bt toxins Cry1Ac and Cry2Ab against the cotton bollworm
To delay evolution of pest resistance to transgenic crops producing insecticidal proteins from Bacillus thuringiensis (Bt), the "pyramid" strategy uses plants that produce two or more toxins that kill the same pe...
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Article
Open AccessCis-mediated down-regulation of a trypsin gene associated with Bt resistance in cotton bollworm
Transgenic plants producing insecticidal proteins from the bacterium Bacillus thuringiensis (Bt) are useful for pest control, but their efficacy is reduced when pests evolve resistance. Here we examined the mecha...
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Open AccessMis-splicing of the ABCC2 gene linked with Bt toxin resistance in Helicoverpa armigera
Toxins from the bacterium Bacillus thuringiensis (Bt) are used widely for insect control in sprays and transgenic plants, but their efficacy is reduced when pests evolve resistance. Previous work showed that muta...
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Open AccessQuantitative Analysis of Fitness Costs Associated with the Development of Resistance to the Bt Toxin Cry1Ac in Helicoverpa armigera
Transgenic Bacillus thuringiensis (Bt) crops play an increasing role in pest control and resistance management is a major issue in large-scale cultivation of Bt crops. The fitness cost of resistance in targeted p...
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Article
Cyclin D1 induction of Dicer governs microRNA processing and expression in breast cancer
Cyclin D1 encodes the regulatory subunit of a holoenzyme that phosphorylates the pRB protein and promotes G1/S cell-cycle progression and oncogenesis. Dicer is a central regulator of miRNA maturation, encoding an...
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Widespread adoption of Bt cotton and insecticide decrease promotes biocontrol services
The widespread use of Bt crops reduces the outbreaks of certain targeted pests and the need for insecticide use, leading to enhanced biocontrol of other potential pest species in the Bt crops; neighbouring non...
