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  1. No Access

    Protocol

    FLP-Map**

    Genetic map** with DNA sequence polymorphisms allows for map-based positional cloning of mutations at any required resolution. Numerous methods have been worked out to assay single nucleotide polymorphisms (...

    Knud Nairz, Peder Zipperlen, Manuel Schneider in Comparative Genomics (2007)

  2. Article

    Open Access

    A universal method for automated gene map**

    Small insertions or deletions (InDels) constitute a ubiquituous class of sequence polymorphisms found in eukaryotic genomes. Here, we present an automated high-throughput genoty** method that relies on the d...

    Peder Zipperlen, Knud Nairz, Ivo Rimann, Konrad Basler, Ernst Hafen… in Genome Biology (2005)

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  3. Article

    Open Access

    A reverse genetic screen in Drosophila using a deletion-inducing mutagen

    We report the use of the cross-linking drug hexamethylphosphoramide (HMPA), which introduces small deletions, as a mutagen suitable for reverse genetics in the model organism Drosophila melanogaster. A compatible...

    Knud Nairz, Peder Zipperlen, Charles Dearolf, Konrad Basler, Ernst Hafen in Genome Biology (2004)

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  4. No Access

    Article

    Meiotic chromosome synapsis in a haploid yeast

    An extensive synaptonemal complex (SC) is found at pachytene in whole mount spread preparations of a haploid yeast, Saccharomyces cerevisiae, strain. Whereas unsynapsed axial elements are present only in a few nu...

    Josef Loidl, Knud Nairz, Franz Klein in Chromosoma (1991)