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    Protocol

    Intact Mass Quantitation of Therapeutic Antibodies for Pharmacokinetic Studies Using Immuno-Purification

    The quantitation of therapeutic antibodies by mass spectrometry often utilizes a surrogate peptide approach following enzymatic digestion of the antibody. Although this approach has been widely adopted, it is ...

    Lisa A. Vasicek, Daniel S. Spellman, Kevin P. Bateman in Therapeutic Antibodies (2022)