8 Result(s)
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Article
The Third International Inflammatory Breast Cancer Conference
Inflammatory breast cancer (IBC) is the most aggressive and deadly form of breast cancer. Disease-specific research and conferences have been organized since 2008 with the intent to bring together experts in v...
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Article
Differential effects of vitamin D treatment on inflammatory and non-inflammatory breast cancer cell lines
Vitamin D is a known regulator of breast cancer cell proliferation, apoptosis, migration, invasion and differentiation in vitro. Recent studies have suggested a preventative role for vitamin D in breast cancer...
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Article
Rho GTPases in PC-3 prostate cancer cell morphology, invasion and tumor cell diapedesis
Background The Rho GTPases comprise one of the eight subfamilies of the Ras superfamily of monomeric GTP-binding proteins and are involved in cytoskeletal organization. Previously, using ...
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Article
Step** out of the flow: capillary extravasation in cancer metastasis
In order for cancer cells to successfully colonize a metastatic site, they must detach from the primary tumor using extracellular matrix-degrading proteases, intravasate and survive in the circulation, evade t...
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Article
The current understanding of the molecular determinants of inflammatory breast cancer metastasis
Inflammatory breast cancer is a highly aggressive and metastatic form of locally advanced breast cancer that carries a significantly worse prognosis than non-inflammatory breast cancers. Unfortunately, the mol...
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Article
Inflammatory breast cancer: Relationship between growth factor signaling and motility in aggressive cancers
A variety of phenotypic characteristics are required for a cancer cell to successfully complete the metastatic cascade. Acquisition of a motile and invasive phenotype is one requirement for a cell to become me...
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Article
Mitogen activated protein kinase pathway is involved in RhoC GTPase induced motility, invasion and angiogenesis in inflammatory breast cancer
Inflammatory breast cancer (IBC) is the most lethal form of locally advanced breast cancer known. IBC carries a guarded prognosis primarily due to rapid onset of disease, typically within six months, and the p...
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Article
Molecular biology of breast cancer metastasis Inflammatory breast cancer: clinical syndrome and molecular determinants
Inflammatory breast cancer (IBC) is an aggressive form of locally advanced breast cancer (LABC) that effects approximately 5% of women with breast cancer annually in the USA. It is a clinically and pathologica...
